Art

J-GLOBAL ID：202002229850689194   Reference number：20A1355875

Research Advances in How the cGAS-STING Pathway Controls the Cellular Inflammatory Response

cGAS-STING経路が細胞炎症反応を制御する方法の研究進展【JST・京大機械翻訳】

Author (4)： Wan Dongshan (Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China) ,  Wan Dongshan (Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China) ,  Jiang Wei (Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China) ,  Hao Junwei (Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China)
Material： Frontiers in Immunology (Web)
Volume： 11  Page： 615  Publication year： 2020 
JST Material Number： U7074A  ISSN： 1664-3224  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Double-stranded DNA (dsDNA) se...

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Thesaurus term： interaction ,  gene ,  interferon ,  *inflammation ,  dyeing ,  cellular signal transduction ,  synthase ,  natural immunity ,  autophagy
Semi thesaurus term： 細胞生存 ,  二本鎖DNA ,  *炎症反応 ,  臨床応用 ,  炎症性疾患 ,  *STING , 【Automatic Indexing@JST】

Author keywords (5)： inflammation ,  cGAS ,  STING ,  cGAMP ,  type I interferonopathies

JST classification (2)： Infectious immunity  (ED03030P) ,  Biophylaxis and immune systems in general  (ED01010F)

Reference (341)：

• Roers A, Hiller B, Hornung V. Recognition of endogenous nucleic acids by the innate immune system. Immunity. (2016) 44:739-54. doi: 10.1016/j.immuni.2016.04.002
• Ishikawa H, Barber GN. STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. Nature. (2008) 455:674-8. doi: 10.1038/nature07317
• Zhong B, Yang Y, Li S, Wang YY, Li Y, Diao F, et al The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation. Immunity. (2008) 29:538-50. doi: 10.1016/j.immuni.2008.09.003
• Sun W, Li Y, Chen L, Chen H, You F, Zhou X, et al ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization. Proc Natl Acad Sci USA. (2009) 106:8653-8. doi: 10.1073/pnas.0900850106
• Woodward JJ, Iavarone AT, Portnoy DA. C-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response. Science. (2010) 328:1703-5. doi: 10.1126/science.1189801

Terms in the title (7)： cGAS ,  STING ,  経路 ,  細胞 ,  炎症反応 ,  研究 ,  進展