Art

J-GLOBAL ID：202002233309641146   Reference number：20A0385045

Antineuropathic pain actions of Wu-tou decoction resulted from the increase of neurotrophic factor and decrease of CCR5 expression in primary rat glial cells

初代ラットグリア細胞における神経栄養因子の増加とCCR5発現の減少から生じるWu-Tou煎剤の抗神経障害性疼痛作用【JST・京大機械翻訳】

Author (9)： Guo Qiuyan (Department of Biochemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan) ,  Guo Qiuyan (Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, 100700, China) ,  Mizuno Koji (Department of Biochemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan) ,  Okuyama Katsuki (Department of Biochemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan) ,  Lin Na (Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, 100700, China) ,  Zhang Yanqiong (Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, 100700, China) ,  Hayashi Hideki (Department of Applied Biochemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan) ,  Takagi Norio (Department of Applied Biochemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan) ,  Sato Takashi (Department of Biochemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan)
Material： Biomedicine & Pharmacotherapy  (Biomedicine and Pharmacotherapy)
Volume： 123  Page： Null  Publication year： 2020 
JST Material Number： A0845C  ISSN： 0753-3322  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Wu-tou decoction (WTD), a clas...

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Thesaurus term： *neurotrophic factor ,  *decoction ,  *Rattus ,  chemokine ,  Chinese drug ,  cytokine ,  gene expression ,  inflammatory cytokine ,  *glia cell ,  *pain ,  analgesic ,  in vitro experiment ,  trigeminal neuralgia ,  *factor ,  *bioactive factor ,  *Myomorpha ,  molecular genetic phenomenon
Semi thesaurus term： BDNF ,  GDNF , 【Automatic Indexing@JST】

Author keywords (4)： Neurotrophic factor ,  C-C chemokine receptor type 5 ,  Wu-tou decoction ,  Antineuropathic pain

JST classification (4)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Basic research of pharmacology of crude drugs  (GX06020J) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Cell physiology in general  (EF02010S)

Terms in the title (7)： ラット ,  グリア細胞 ,  神経栄養因子 ,  CCR5 ,  発現 ,  煎剤 ,  神経障害性疼痛