Art

J-GLOBAL ID：202002234116885202   Reference number：20A0559469

Utilization of the chronic atrioventricular block cynomolgus monkey as an in vivo model to evaluate drug interaction-associated torsade de pointes

薬物相互作用関連トルサード・ド・ポワントを評価するための,in vivoモデルとしての慢性房室ブロックカニクイザルの利用

Author (12)： Goto Ai (Department of Pharmacology, Toho University Graduate School of Medicine, 5-21-16 Omori-nishi, Ota-ku, Tokyo, 143-8540, Japan) ,  Sakamoto Kengo (Ina Research Inc., 2148-188 Nishiminowa, Ina-shi, Nagano, 399-4501, Japan) ,  Hagiwara-Nagasawa Mihoko (Department of Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-nishi, Ota-ku, Tokyo, 143-8540, Japan) ,  Kambayashi Ryuichi (Department of Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-nishi, Ota-ku, Tokyo, 143-8540, Japan) ,  Chiba Koki (Department of Pharmacology, Toho University Graduate School of Medicine, 5-21-16 Omori-nishi, Ota-ku, Tokyo, 143-8540, Japan) ,  Nunoi Yoshio (Department of Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-nishi, Ota-ku, Tokyo, 143-8540, Japan) ,  Izumi-Nakaseko Hiroko (Department of Pharmacology, Toho University Graduate School of Medicine, 5-21-16 Omori-nishi, Ota-ku, Tokyo, 143-8540, Japan) ,  Izumi-Nakaseko Hiroko (Department of Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-nishi, Ota-ku, Tokyo, 143-8540, Japan) ,  Matsumoto Akio (Department of Aging Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-nishi, Ota-ku, Tokyo, 143-8540, Japan) ,  Sugiyama Atsushi (Department of Pharmacology, Toho University Graduate School of Medicine, 5-21-16 Omori-nishi, Ota-ku, Tokyo, 143-8540, Japan) ,  Sugiyama Atsushi (Department of Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-nishi, Ota-ku, Tokyo, 143-8540, Japan) ,  Sugiyama Atsushi (Department of Aging Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-nishi, Ota-ku, Tokyo, 143-8540, Japan)
Material： Journal of Pharmacological Sciences (Web)  (J Pharmacol Sci (Web))
Volume： 142  Issue： 4  Page： 172-175  Publication year： 2020 
JST Material Number： U0667A  ISSN： 1347-8613  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： atrioventricular block ,...
Semi thesaurus term： *Torsades de Pointes ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=20A0559469&from=J-GLOBAL&jstjournalNo=U0667A") }}

Author keywords (3)： Cynomolgus monkey ,  Drug interaction ,  Torsade de pointes

JST classification (2)： Basic medicine on cardiovascular system  (GJ01020K) ,  Interactions of drugs  (GV01070X)

Substance index (2)： Ketoconazole ,  Terfenadine

Terms in the title (7)： 薬物相互作用 ,  トルサード・ド・ポワント ,  評価 ,  モデル ,  慢性 ,  房室ブロック ,  カニクイザル