Art

J-GLOBAL ID：202002235537924916   Reference number：20A0537711

Nanoparticle Drug Delivery Can Reduce the Hepatotoxicity of Therapeutic Cargo

ナノ粒子ドラッグデリバリーは治療用貨物の肝毒性を減少させることができる【JST・京大機械翻訳】

Author (22)： Yang Feifei (Institute of Medicinal Plant Development (IMPLAD), Chinese Academy of Medical Sciences & Peking Union Medical College, Haidian District, Beijing, 100193, P. R. China) ,  Yang Feifei (Laboratory of Nano- and Translational Medicine, Lineberger Comprehensive Cancer Center, Carolina Center for Cancer Nanotechnology Excellence, Carolina Institute of Nanomedicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Yang Feifei (Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Medik Yusra (Laboratory of Nano- and Translational Medicine, Lineberger Comprehensive Cancer Center, Carolina Center for Cancer Nanotechnology Excellence, Carolina Institute of Nanomedicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Medik Yusra (Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Li Liantao (Laboratory of Nano- and Translational Medicine, Lineberger Comprehensive Cancer Center, Carolina Center for Cancer Nanotechnology Excellence, Carolina Institute of Nanomedicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Li Liantao (Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Li Liantao (Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Cancer Institute, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, P. R. China) ,  Tian Xi (Laboratory of Nano- and Translational Medicine, Lineberger Comprehensive Cancer Center, Carolina Center for Cancer Nanotechnology Excellence, Carolina Institute of Nanomedicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Tian Xi (Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Fu Dong (UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Brouwer Kim L. R. (UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Wagner Kyle (Laboratory of Nano- and Translational Medicine, Lineberger Comprehensive Cancer Center, Carolina Center for Cancer Nanotechnology Excellence, Carolina Institute of Nanomedicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Wagner Kyle (Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Sun Bo (Laboratory of Nano- and Translational Medicine, Lineberger Comprehensive Cancer Center, Carolina Center for Cancer Nanotechnology Excellence, Carolina Institute of Nanomedicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Sun Bo (Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Sendi Hossein (Laboratory of Nano- and Translational Medicine, Lineberger Comprehensive Cancer Center, Carolina Center for Cancer Nanotechnology Excellence, Carolina Institute of Nanomedicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Sendi Hossein (Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Mi Yu (Laboratory of Nano- and Translational Medicine, Lineberger Comprehensive Cancer Center, Carolina Center for Cancer Nanotechnology Excellence, Carolina Institute of Nanomedicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Mi Yu (Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Wang Andrew Z. (Laboratory of Nano- and Translational Medicine, Lineberger Comprehensive Cancer Center, Carolina Center for Cancer Nanotechnology Excellence, Carolina Institute of Nanomedicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Wang Andrew Z. (Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA)
Material： Small
Volume： 16  Issue： 7  Page： e1906360  Publication year： 2020 
JST Material Number： W2348A  ISSN： 1613-6810  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Hepatotoxicity is a key concer...

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Thesaurus term： macrophage ,  *cargo ,  *drug delivery system ,  *hepatic toxicity ,  *nano particle ,  small molecule
Semi thesaurus term： 臨床研究 , 【Automatic Indexing@JST】

Author keywords (5)： clinical translation ,  hepatotoxicity ,  macrophage uptake ,  nanomedicine ,  nanotoxicity

JST classification (2)： Medical materials  (GA05040H) ,  Basic biopharmacy  (GY01021U)

Terms in the title (5)： ナノ粒子 ,  ドラッグデリバリー ,  治療 ,  貨物 ,  肝毒性