Art

J-GLOBAL ID：202002235614781899   Reference number：20A1757589

Regulated IFN signalling preserves the stemness of intestinal stem cells by restricting differentiation into secretory-cell lineages

調節性IFNシグナル伝達は分泌細胞系列への分化を制限することにより腸幹細胞の幹細胞性を維持する【JST・京大機械翻訳】

Author (13)： Sato Taku (Department of Biodefense Research, Medical Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Sato Taku (PRESTO, Japan Science and Technology Agency, Saitama, Japan) ,  Ishikawa Shun (Department of Biodefense Research, Medical Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Asano Jumpei (Department of Biodefense Research, Medical Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Yamamoto Hirona (Department of Biodefense Research, Medical Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Fujii Masayuki (Department of Surgical Oncology, The University of Tokyo, Tokyo, Japan) ,  Fujii Masayuki (Department of Organoid Medicine, Keio University School of Medicine, Tokyo, Japan) ,  Sato Toshiro (Department of Organoid Medicine, Keio University School of Medicine, Tokyo, Japan) ,  Yamamoto Kouhei (Department of Comprehensive Pathology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Kitagaki Keisuke (Division of Surgical Pathology, Tokyo Medical and Dental University Hospital, Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Akashi Takumi (Division of Surgical Pathology, Tokyo Medical and Dental University Hospital, Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Okamoto Ryuichi (Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan) ,  Ohteki Toshiaki (Department of Biodefense Research, Medical Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan)
Material： Nature Cell Biology  (Nat Cell Biol)
Volume： 22  Issue： 8  Page： 919-926  Publication year： 2020 
JST Material Number： W1369A  ISSN： 1465-7392  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Abstract: Intestinal stem cell...

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Thesaurus term： interferon ,  *differentiation (biology) ,  lymphocyte ,  completeness ,  Paneth Cells ,  crypt ,  Gut epithelium ,  *secretory cell ,  *intestinal stem cell ,  *Signal Transduction ,  nitrogen heterocyclic compound ,  organofluorine compound ,  urea compound ,  hydroxy compound
Semi thesaurus term： *cellular signal transduction , 【Automatic Indexing@JST】

JST classification (2)： Cell physiology in general  (EF02010S) ,  Biological function  (EB03040U)

Substance index (1)： Fluorouracil

Terms in the title (9)： 調節 ,  IFN ,  シグナル伝達 ,  分泌 ,  細胞系列 ,  分化 ,  制限 ,  腸幹細胞 ,  幹細胞性