Art

J-GLOBAL ID：202002237272666160   Reference number：20A1356567

Gut Microbiome Reveals Specific Dysbiosis in Primary Osteoporosis

腸マイクロバイオームは原発性骨粗鬆症における特異的ジストビオーシスを明らかにする【JST・京大機械翻訳】

Author (12)： Xu Zhiming (Department of Orthopaedics, First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China) ,  Xie Zheng (Department of Orthopaedics, First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China) ,  Sun Jianguang (Department of Orthopaedics, First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China) ,  Huang Shilei (Department of Orthopaedics, First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China) ,  Chen Yangyang (Department of Orthopaedics, First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China) ,  Li Chengxiang (Department of Orthopaedics, First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China) ,  Sun Xing (Department of Orthopaedics, First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China) ,  Xia Bicheng (Department of Orthopaedics, First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China) ,  Tian Lingyang (Department of Orthopaedics, First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China) ,  Guo Caijuan (Department of Orthopaedics, First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China) ,  Li Feng (Department of Orthopaedics, First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China) ,  Pi Guofu (Department of Orthopaedics, First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China)
Material： Frontiers in Cellular and Infection Microbiology (Web)
Volume： 10  Page： 160  Publication year： 2020 
JST Material Number： U7063A  ISSN： 2235-2988  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Object: Primary osteoporosis (...

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Thesaurus term： algorithm ,  micro structure ,  information processing ,  microorganism ,  heredity ,  biological activity ,  *flora ,  microflora ,  bone disease ,  biomarker ,  bone metabolism ,  bone density
Semi thesaurus term： Dialister ,  免疫系 ,  骨組織 , 【Automatic Indexing@JST】

Author keywords (5)： primary osteoporosis ,  gut microbiome ,  16s rDNA ,  metagenomic analysis ,  biomarker

JST classification (3)： Digestive system diseases  (GH03000W) ,  Musculoskeletal diseases  (GG03000T) ,  Immunologic diseases,allergic diseases in general.  (GD04010C)

Reference (46)：

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• Belzer C., Chia L. W., Aalvink S., Chamlagain B., Piironen V., Knol J., et al. (2017). Microbial metabolic networks at the mucus layer lead to diet-independent butyrate and Vitamin B12 production by intestinal symbionts. MBio 8:e00770-17. doi: 10.1128/mBio.00770-17
• Biver E., Berenbaum F., Valdes A. M., Araujo De Carvalho I., Bindels L. B., Brandi M. L., et al. (2019). Gut microbiota and osteoarthritis management: an expert consensus of the European society for clinical and economic aspects of osteoporosis, osteoarthritis and musculoskeletal diseases (ESCEO). Ageing Res. Rev. 55:100946. doi: 10.1016/j.arr.2019.100946
• Black D. M., Rosen C. J. (2016). Clinical practice. Postmenopausal osteoporosis. N. Engl. J. Med. 374, 254-262. doi: 10.1056/NEJMcp1513724
• Brown C. (2017). Osteoporosis: staying strong. Nature 550, S15-S17. doi: 10.1038/550S15a

Terms in the title (3)： 腸 ,  マイクロバイオーム ,  原発性骨粗鬆症