Art

J-GLOBAL ID：202002238144693667   Reference number：20A0463810

卵巣癌に対するPARP阻害薬

Author (1)： FUKUDA TAKESHI (大阪市大 大学院医学研究科 女性病態医学)
Material： 産婦人科の進歩  (Advances in Obstetrics and Gynecology)
Volume： 72  Issue： 1  Page： 50-52  Publication year： Feb. 01, 2020 
JST Material Number： Z0452B  ISSN： 0370-8446  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： human(primates) ,...
Semi thesaurus term： Genes, BRCA2 ,...

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JST classification (3)： Tumors(=neoplasms)of female genitalia and fetus  (GS04000K) ,  Drug therapy(=pharmacotherapy)for digestive system diseases  (GH05020G) ,  Clinical application of antitumor(=antineoplastic)drugs  (GW16020L)

Substance index (1)： Olaparib

Reference (11)：

• 1) Heintz AP, Odicino F, Maisonneuve P, et al. : Carcinoma of the ovary. FIGO 26th Annual Report on the Results of Treatment in Gynecological Cancer. Int J Gynaecol Obstet, 95 Suppl 1 : S161-192, 2006.
• 2) GENEReviews : http://www.ncbi.nlm.nih.gov/books/NBK1247/
• 3) Chen S, Parmigiani G : Meta-analysis of BRCA1 and BRCA2 penetrance. J Clin Oncol, 25 : 1329-1333, 2007.
• 4) Miki Y, Swensen J, Stattuck-Eidens D, et al. : A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science, 266 : 66-71, 1994.
• 5) Yoshida K, Miki Y : Role of BRCA1 and BRCA2 as regulators of DNA repair, transcription, and cell cycle in response to DNA damage. Cancer Sci, 95 : 866-871, 2004.

Terms in the title (3)： 卵巣癌 ,  PARP ,  阻害薬