Art

J-GLOBAL ID：202002239413684791   Reference number：20A0328800

Integrating Duodenal Sampling in a Human Mass Balance Study to Quantify the Elimination Pathways of JNJ-53718678, a Respiratory Syncytial Virus Fusion Protein Inhibitor

呼吸器合胞体ウイルス融合蛋白質阻害剤JNJ-53718678の除去経路を定量化するためのヒト物質収支研究における十二指腸サンプリングの統合【JST・京大機械翻訳】

Author (8)： Remmerie Bart (Global Clinical Pharmacology, Janssen Research & Development, Beerse, Belgium) ,  van den Boer Maarten (Clinical Pharmacology Unit, Janssen Research & Development, Merksem, Belgium) ,  Van Looy Thomas (Clinical Pharmacology Unit, Janssen Research & Development, Merksem, Belgium) ,  Wynant Inneke (Drug Metabolism and Pharmacokinetics, Janssen Research & Development, Beerse, Belgium) ,  Rusch Sarah (Statistical Decision and Sciences, Janssen Biostatistics Research & Development, Beerse, Belgium) ,  Huntjens Dymphy (Global Clinical Pharmacology, Janssen Research & Development, Beerse, Belgium) ,  De Meulder Marc (Drug Metabolism and Pharmacokinetics, Janssen Research & Development, Beerse, Belgium) ,  Stevens Marita (Global Clinical Development Infectious Diseases, Janssen Research & Development, Beerse, Belgium)
Material： Advances in Therapy
Volume： 37  Issue： 1  Page： 578-591  Publication year： 2020 
JST Material Number： W4004A  ISSN： 1865-8652  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Abstract: Introduction: The s...

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Thesaurus term： gallbladder ,  infectious disease ,  plasma(blood) ,  *material balance ,  *respiratory organ ,  *duodenum ,  clearance ,  metabolic pathway ,  *human(primates) ,  metabolite ,  animal ,  glucuronic acid conjugation ,  in vitro experiment ,  radioactivity ,  biliary excretion

Author keywords (5)： Duodenal fluid sampling ,  Infectious disease ,  JNJ-53718678 ,  Mass balance ,  Respiratory syncytial virus

JST classification (2)： Microorganism biochemistry  (EG03020N) ,  Antibiotics in general  (GX01000E)

Terms in the title (11)： 呼吸器 ,  合胞体 ,  ウイルス融合蛋白質阻害剤 ,  経路 ,  定量化 ,  ヒト ,  物質収支 ,  研究 ,  十二指腸 ,  サンプリング ,  統合