Art

J-GLOBAL ID：202002240433708457   Reference number：20A0497761

Tuft Cell Formation Reflects Epithelial Plasticity in Pancreatic Injury: Implications for Modeling Human Pancreatitis

TufT細胞形成は膵臓損傷における上皮可塑性を反映する:ヒト膵炎のモデリングに対する意味【JST・京大機械翻訳】

Author (10)： DelGiorno Kathleen E. (Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, United States) ,  Naeem Razia F. (Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, United States) ,  Fang Linjing (Waitt Advanced Biophotonics Center, Salk Institute for Biological Studies, La Jolla, CA, United States) ,  Chung Chi-Yeh (Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, United States) ,  Ramos Cynthia (Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, United States) ,  Luhtala Natalie (Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, United States) ,  O'Connor Carolyn (Flow Cytometry Core, Salk Institute for Biological Studies, La Jolla, CA, United States) ,  Hunter Tony (Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, United States) ,  Manor Uri (Waitt Advanced Biophotonics Center, Salk Institute for Biological Studies, La Jolla, CA, United States) ,  Wahl Geoffrey M. (Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, United States)
Material： Frontiers in Physiology (Web)
Volume： 11  Page： 88  Publication year： 2020 
JST Material Number： U7093A  ISSN： 1664-042X  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Chronic pancreatitis, a known ...

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Thesaurus term： *plasticity ,  Inflammation ,  Mutation ,  tumor cell ,  *pancreatitis ,  carcinogenicity ,  *human ,  *epithelium ,  heterogeneity ,  inflammation mediator ,  Heredity ,  fibrous disease ,  risk factor ,  resolving power ,  pipe line ,  *mechanical property ,  *property ,  *membrane and film ,  *histomembrane

Author keywords (5)： tuft cells ,  Dclk1 ,  pancreatitis ,  metaplasia ,  mouse models

JST classification (2)： Basic medicine on digestive system  (GH01020E) ,  Cytokines  (EB08090G)

Reference (42)：

• Bailey J. M., Alsina J., Rasheed Z. A., McAllister F. M., Fu Y. Y., Plentz R., et al (2014). DCLK1 marks a morphologically distinct subpopulation of cells with stem cell properties in preinvasive pancreatic cancer. Gastroenterology 146 245-256. doi: 10.1053/j.gastro.2013.09.050
• Benatar T., Cao M. Y., Lee Y., Lightfoot J., Feng N., Gu X., et al (2010). IL-17E, a proinflammatory cytokine, has antitumor efficacy against several tumor types in vivo. Cancer Immunol. Immunother. 59 805-817. doi: 10.1007/s00262-009-0802-8
• Bezencon C., Furholz A., Raymond F., Mansourian R., Metairon S., Le Coutre J., et al (2008). Murine intestinal cells expressing Trpm5 are mostly brush cells and express markers of neuronal and inflammatory cells. J. Comp. Neurol. 509 514-525. doi: 10.1002/cne.21768
• Bindea G., Mlecnik B., Hackl H., Charoentong P., Tosolini M., Kirilovsky A., et al (2009). ClueGO: a cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks. Bioinformatics 25 1091-1093. doi: 10.1093/bioinformatics/btp101
• Bornstein C., Nevo S., Giladi A., Kadouri N., Pouzolles M., Gerbe F., et al (2018). Single-cell mapping of the thymic stroma identifies IL-25-producing tuft epithelial cells. Nature 559 622-626. doi: 10.1038/s41586-018-0346-1

Terms in the title (8)： Tuft細胞 ,  膵臓損傷 ,  上皮 ,  可塑性 ,  ヒト ,  膵炎 ,  モデリング ,  意味