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J-GLOBAL ID：202002242357796102   Reference number：20A2090421

The Critical Roles and Mechanisms of Immune Cell Death in Sepsis

Sepsisにおける免疫細胞死の重要な役割とメカニズム【JST・京大機械翻訳】

Author (12)： Cheng Zhenxing (Department of Clinical Infection, Microbiology and Immunology, Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom) ,  Cheng Zhenxing (Medical School, Southeast University, Nanjing, China) ,  Abrams Simon T. (Department of Clinical Infection, Microbiology and Immunology, Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom) ,  Toh Julien (Wirral University Teaching Hospitals NHS Foundation Trust, Wirral, United Kingdom) ,  Wang Susan Siyu (Royal London Hospital, London, United Kingdom) ,  Wang Zhi (Medical School, Southeast University, Nanjing, China) ,  Yu Qian (Medical School, Southeast University, Nanjing, China) ,  Yu Weiping (Medical School, Southeast University, Nanjing, China) ,  Toh Cheng-Hock (Department of Clinical Infection, Microbiology and Immunology, Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom) ,  Toh Cheng-Hock (Liverpool University Hospitals NHS Foundation Trust, Liverpool, United Kingdom) ,  Wang Guozheng (Department of Clinical Infection, Microbiology and Immunology, Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom) ,  Wang Guozheng (Medical School, Southeast University, Nanjing, China)
Material： Frontiers in Immunology (Web)
Volume： 11  Page： 1918  Publication year： 2020 
JST Material Number： U7074A  ISSN： 1664-3224  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Sepsis was first described by ...

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Thesaurus term： *death ,  mortality ,  protein ,  histone ,  immunosuppression ,  septicemia ,  neutrophils ,  targeting ,  therapeutic planning ,  multiple organ failure ,  systemic inflammatory response syndrome ,  bacterial infection(disease)
Semi thesaurus term： *Sepsis ,  HMGB1蛋白質 ,  分子機構 ,  *免疫細胞 , 【Automatic Indexing@JST】

Author keywords (6)： sepsis ,  extensive immune cell death ,  damage-associated molecular patterns (DAMPs) ,  multiple organ dysfunction syndrome (MODS) ,  extracellular histones ,  immunosuppression

JST classification (1)： Infectious diseases,parasitics diseases in general.  (GD01010H)

Reference (159)：

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• Gabrilovich DI. Myeloid-derived suppressor cells. Cancer Immunol Res. (2017) 5:3-8. doi: 10.1158/2326-6066.CIR-16-0297
• Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med. (2001) 29:1303-10. doi: 10.1097/00003246-200107000-00002
• Rhee C, Jones TM, Hamad Y, Pande A, Varon J, O'Brien C, et al. Prevalence, underlying causes, and preventability of sepsis-associated mortality in US Acute Care Hospitals. JAMA Netw Open. (2019) 2:e187571. doi: 10.1001/jamanetworkopen.2018.7571
• Hunt A. Sepsis: an overview of the signs, symptoms, diagnosis, treatment and pathophysiology. Emerg Nurse. (2019) 27:32-41. doi: 10.7748/en.2019.e1926

Terms in the title (4)： 免疫 ,  細胞死 ,  役割 ,  メカニズム