Art

J-GLOBAL ID：202002242414598182   Reference number：20A1323045

Mouse Bone Marrow-derived Microglia-like Cells Secrete Transforming Growth Factor-β1 and Promote Microglial Aβ Phagocytosis and Reduction of Brain Aβ

マウス骨髄由来ミクログリア様細胞は形質転換成長因子β1を分泌し,ミクログリアAβ食作用と脳Aβの減少を促進する【JST・京大機械翻訳】

Author (17)： Kuroda Eriko (Department of Clinical and Translational Physiology, Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8414, Japan) ,  Nishimura Kaneyasu (Division of Integrated Pharmaceutical Sciences, Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8414, Japan) ,  Kawanishi Shohei (Department of Clinical and Translational Physiology, Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8414, Japan) ,  Kawanishi Shohei (Division of Integrated Pharmaceutical Sciences, Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8414, Japan) ,  Sueyoshi Mari (Department of Clinical and Translational Physiology, Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8414, Japan) ,  Ueno Fumitaka (Department of Clinical and Translational Physiology, Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8414, Japan) ,  Toji Yumiko (Department of Clinical and Translational Physiology, Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8414, Japan) ,  Abo Naoko (Department of Clinical and Translational Physiology, Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8414, Japan) ,  Konishi Toko (Department of Clinical and Translational Physiology, Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8414, Japan) ,  Harada Koki (Division of Integrated Pharmaceutical Sciences, Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8414, Japan) ,  Satake Shiho (Division of Integrated Pharmaceutical Sciences, Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8414, Japan) ,  Shima Chiaki (Division of Integrated Pharmaceutical Sciences, Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8414, Japan) ,  Toda Yuki (Department of Clinical and Translational Physiology, Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8414, Japan) ,  Kitamura Yoshihisa (Laboratory of Pharmacology and Neurobiology, College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Shiga 525-8577, Japan) ,  Shimohama Shun (Department of Neurology, Sapporo Medical University, School of Medicine, Sapporo 060-8543, Japan) ,  Ashihara Eishi (Department of Clinical and Translational Physiology, Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8414, Japan) ,  Takata Kazuyuki (Division of Integrated Pharmaceutical Sciences, Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8414, Japan)
Material： Neuroscience
Volume： 438  Page： 217-228  Publication year： 2020 
JST Material Number： T0919A  ISSN： 0306-4522  CODEN： NRSCDN  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Accumulation of amyloid-β (Aβ)...

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Thesaurus term： interaction ,  amyloid ,  *bone marrow ,  receptor ,  *phagocytosis ,  hippocampus ,  Alzheimer disease ,  cytokine ,  TGF beta ,  *microglia ,  amyloid beta-protein
Semi thesaurus term： 認知障害 ,  *TGFβ1 ,  脳組織 ,  マウスモデル , 【Automatic Indexing@JST】

Author keywords (6)： Alzheimer’s disease ,  amyloid-β ,  microglia ,  bone marrow-derived microglia-like cells ,  transforming growth factor-β1 ,  Smad2/3

JST classification (2)： Basic neurology  (GN01020W) ,  Central nervous system  (EJ12030F)

Terms in the title (9)： マウス ,  骨髄 ,  ミクログリア ,  細胞 ,  形質転換成長因子β1 ,  分泌 ,  食作用 ,  脳 ,  促進