Art

J-GLOBAL ID：202002242802325099   Reference number：20A0537808

Lamin A/C negatively regulated by miR-124-3p modulates apoptosis of vascular smooth muscle cells during cyclic stretch application in rats

miR-124-3pによって負に調節されるラミンA/Cはラットにおける周期的伸長適用時の血管平滑筋細胞のアポトーシスを調節する【JST・京大機械翻訳】

Author (12)： Bao Han (Institute of Mechanobiology & Medical Engineering, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, China) ,  Li Hai-Peng (Institute of Mechanobiology & Medical Engineering, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, China) ,  Shi Qian (Institute of Mechanobiology & Medical Engineering, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, China) ,  Huang Kai (Institute of Mechanobiology & Medical Engineering, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, China) ,  Chen Xiao-Hu (Institute of Mechanobiology & Medical Engineering, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, China) ,  Chen Yuan-Xiu (Institute of Mechanobiology & Medical Engineering, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, China) ,  Han Yue (Institute of Mechanobiology & Medical Engineering, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, China) ,  Xiao Qian (Institute of Mechanobiology & Medical Engineering, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, China) ,  Yao Qing-Ping (Institute of Mechanobiology & Medical Engineering, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, China) ,  Qi Ying-Xin (Institute of Mechanobiology & Medical Engineering, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, China) ,  Qi Ying-Xin (Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing, China) ,  Qi Ying-Xin (Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, China)
Material： Acta Physiologica  (Acta Physiol)
Volume： 228  Issue： 3  Page： e13374  Publication year： 2020 
JST Material Number： E0651A  ISSN： 1748-1708  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： AIM: Apoptosis of vascular smo...

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Thesaurus term： protein ,  down-regulation ,  hypertension ,  ELISA ,  quantitative polymerase chain reaction ,  autophagy ,  *rat ,  in vitro experiment ,  luciferase ,  *vascular smooth muscle cell ,  *apoptosis ,  transcription factor ,  vascular remodeling ,  Western blotting ,  drawing(extension)

Author keywords (5)： apoptosis ,  cyclic stretch ,  lamin A/C ,  mechanobiology ,  vascular smooth muscle cells

JST classification (1)： Basic medicine on cardiovascular system  (GJ01020K)

Terms in the title (6)： miR-124 ,  調節 ,  ラミンA ,  ラット ,  血管平滑筋細胞 ,  アポトーシス