Art

J-GLOBAL ID：202002243093862600   Reference number：20A1259074

LidNA, a miRNA inhibitor constructed with unmodified DNA, requires an xxxA insertion sequence in miRNA binding site for its potent inhibitory activity

非修飾DNAで構築されたmiRNA阻害剤Lidnaはその強力な阻害活性に対するmiRNA結合部位におけるXXXA挿入配列を必要とする【JST・京大機械翻訳】

Author (4)： Tachibana Akira (Department of Bioengineering, Graduate School of Engineering, Osaka City University, Japan, Osaka) ,  Saito Satoshi (Department of Bioengineering, Graduate School of Engineering, Osaka City University, Japan, Osaka) ,  Fujiyama Yukiko (Department of Bioengineering, Graduate School of Engineering, Osaka City University, Japan, Osaka) ,  Tanabe Toshizumi (Department of Bioengineering, Graduate School of Engineering, Osaka City University, Japan, Osaka)
Material： FEBS Letters  (for the Rapid Publication of Short Reports in Biochemistry, Biophysics)
Volume： 594  Issue： 10  Page： 1608-1614  Publication year： 2020 
JST Material Number： D0575A  ISSN： 0014-5793  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： The involvement of miRNAs in t...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=20A1259074&from=J-GLOBAL&jstjournalNo=D0575A") }}

Thesaurus term： methylation ,  *DNA ,  *RNA ,  *binding site ,  *insertion sequence ,  pathogenesis
Semi thesaurus term： *マイクロRNA ,  *阻害活性 ,  ロック核酸 , 【Automatic Indexing@JST】

Author keywords (6)： argonaute ,  G-quartet structure ,  LidNA ,  miRNA ,  miRNA inhibitor ,  RISC

JST classification (2)： Plant biochemistry  (EH01050J) ,  Gene expression  (EC02040Q)

Terms in the title (8)： 修飾 ,  DNA ,  構築 ,  miRNA ,  阻害剤 ,  阻害活性 ,  結合部位 ,  挿入配列