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J-GLOBAL ID：202002243658614059   Reference number：20A0671083

Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein

改変ヘテロ三量体G蛋白質と共役したヒトPAC1受容体の低温EM構造【JST・京大機械翻訳】

Author (7)： Kobayashi Kazuhiro (Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo, Tokyo, Japan) ,  Shihoya Wataru (Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo, Tokyo, Japan) ,  Nishizawa Tomohiro (Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo, Tokyo, Japan) ,  Kadji Francois Marie Ngako (Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, Japan) ,  Aoki Junken (Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, Japan) ,  Inoue Asuka (Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, Japan) ,  Nureki Osamu (Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo, Tokyo, Japan)
Material： Nature Structural & Molecular Biology  (Nat Struct Mol Biol)
Volume： 27  Issue： 3  Page： 274-280  Publication year： 2020 
JST Material Number： W0637A  ISSN： 1545-9993  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Abstract: Pituitary adenylate ...

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Thesaurus term： peptide ,  adenylate cyclase ,  *protein ,  *conjugation ,  *human(primates) ,  peptide hormone ,  psychotic disorder ,  gene manipulation ,  PACAP ,  *receptor ,  neuropeptide ,  *low temperature ,  polypeptide ,  affinity ,  complex(substance)

JST classification (1)： Gene expression  (EC02040Q)

Terms in the title (7)： 改変 ,  ヘテロ三量体G蛋白質 ,  共役 ,  ヒト ,  PAC1受容体 ,  低温 ,  EM