Art

J-GLOBAL ID：202002243783827342   Reference number：20A2066646

New insights into immunomodulation via overexpressing lipoic acid synthase as a therapeutic potential to reduce atherosclerosis

アテローム性動脈硬化症を減少させる治療の可能性としてのリポ酸シンターゼ過剰発現を介した免疫調節への新しい洞察【JST・京大機械翻訳】

Author (14)： Tian Shaomin (Department of Microbiology & Immunology, University of North Carolina, Chapel Hill, NC 27599, USA) ,  Nakamura Jun (Laboratory of Laboratory Animal Science, Graduate School of Life and Environmental Biosciences, Osaka Prefecture University, Izumisano, Japan) ,  Hiller Sylvia (Department of Comparative Medicine, University of North Carolina, Chapel Hill, NC 27599, USA) ,  Simington Stephen (Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, USA) ,  Holley Darcy W. (Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA) ,  Mota Roberto (Department of Comparative Medicine, University of North Carolina, Chapel Hill, NC 27599, USA) ,  Willis Monte S. (Indiana Center for Musculoskeletal Health, Department of Pathology & Laboratory Medicine, and Krannert Institute of Cardiology and Division of Cardiology, Department of Internal Medicine, Indiana University School of Medicine, 635 Barnhill Drive, Van Nuys MS 5067, Indianapolis, IN 46202, ...) ,  Bultman Scott J. (Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA) ,  Luft J. Christopher (Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, USA) ,  DeSimone Joseph M. (Department of Chemistry, University of North Carolina, Chapel Hill, NC 27599, USA) ,  Jia Zhenquan (Department of Biology, University of North Carolina at Greensboro, Greensboro, NC 27402, USA) ,  Maeda Nobuyo (Department of Comparative Medicine, University of North Carolina, Chapel Hill, NC 27599, USA) ,  Yi Xianwen (Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, USA) ,  Yi Xianwen (McAllister Heart Institute, University of North Carolina, Chapel Hill, NC 27599, USA)
Material： Vascular Pharmacology  (Vasc Pharmacol)
Volume： 133-134  Page： Null  Publication year： 2020 
JST Material Number： D0170C  ISSN： 1537-1891  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Atherosclerosis is a systemic ...

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Thesaurus term： immersional wetting ,  gene ,  antioxidant ,  *Arteriosclerosis ,  oxidation-reduction reaction ,  T cell ,  autoantibody ,  *Atherosclerosis ,  therapeutic planning ,  *synthase ,  antioxidants ,  endogenous ,  *overexpression ,  immune response ,  carboxylic acid ,  sulfur heterocyclic compound
Semi thesaurus term： immunological reaction , 【Automatic Indexing@JST】

Author keywords (5)： Regulatory T cells ,  Oxidized LDL autoantibody ,  Antioxidant mouse models ,  Atherosclerosis ,  And immune regulation

JST classification (1)： Basic medicine on cardiovascular system  (GJ01020K)

Substance index (1)： Lipoic acid

Terms in the title (8)： アテローム性動脈硬化症 ,  治療 ,  可能性 ,  リポ酸 ,  シンターゼ ,  過剰発現 ,  免疫調節 ,  洞察