Art

J-GLOBAL ID：202002244001009061   Reference number：20A0200959

53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination

53BP1は相同組換えにおいて異なる前および切除後ブロックを強制する【JST・京大機械翻訳】

Author (20)： Callen Elsa (Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD 20892, USA) ,  Zong Dali (Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD 20892, USA) ,  Wu Wei (Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD 20892, USA) ,  Wong Nancy (Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD 20892, USA) ,  Stanlie Andre (Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD 20892, USA) ,  Ishikawa Momoko (Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD 20892, USA) ,  Pavani Raphael (Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD 20892, USA) ,  Dumitrache Lavinia C. (Department of Genetics, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA) ,  Byrum Andrea K. (Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO 63110, USA) ,  Mendez-Dorantes Carlos (Department of Cancer Genetics and Epigenetics, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA) ,  Martinez Paula (Telomeres and Telomerase Group, Molecular Oncology Program, Spanish National Cancer Center, Madrid 28029, Spain) ,  Canela Andres (Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD 20892, USA) ,  Maman Yaakov (Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD 20892, USA) ,  Day Amanda (Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD 20892, USA) ,  Kruhlak Michael J. (Laboratory of Cancer Biology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA) ,  Blasco Maria A. (Telomeres and Telomerase Group, Molecular Oncology Program, Spanish National Cancer Center, Madrid 28029, Spain) ,  Stark Jeremy M. (Department of Cancer Genetics and Epigenetics, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA) ,  Mosammaparast Nima (Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO 63110, USA) ,  McKinnon Peter J. (Department of Genetics, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA) ,  Nussenzweig Andre (Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD 20892, USA)
Material： Molecular Cell  (Mol Cell)
Volume： 77  Issue： 1  Page： 26-38.e7  Publication year： 2020 
JST Material Number： W1167A  ISSN： 1097-2765  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： 53BP1 activity drives genome i...

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Thesaurus term： *homologous recombination ,  targeting ,  DNA lesion ,  interaction ,  complex (substance) ,  single-stranded DNA ,  filament ,  blocking effect ,  DNA ,  phosphorylation ,  Genomic Instability ,  BRCA1 Protein ,  *53BP1 ,  Rad51 Recombinase ,  *molecular genetic phenomenon
Semi thesaurus term： RAD51 ,  致死性 , 【Automatic Indexing@JST】

Author keywords (8)： homologous recombination ,  shieldin ,  BRCA1 ,  resection ,  cancer ,  aging ,  PARPi ,  53BP1

JST classification (2)： Molecular genetics in general  (EC02010J) ,  Biological function  (EB03040U)

Terms in the title (3)： 53BP1 ,  相同組換え ,  強制