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J-GLOBAL ID：202002244050955705   Reference number：20A1607950

TNF-α enhances TGF-β-induced endothelial-to-mesenchymal transition via TGF-β signal augmentation

TNF-αはTGF-βシグナルの増強を介してTGF-β誘導内皮間葉転換を促進する

Author (12)： Yoshimatsu Yasuhiro (Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan) ,  Yoshimatsu Yasuhiro (Division of Pharmacology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan) ,  Wakabayashi Ikumi (Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan) ,  Kimuro Shiori (Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan) ,  Takahashi Naoya (Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan) ,  Takahashi Kazuki (Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan) ,  Kobayashi Miho (Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan) ,  Maishi Nako (Department of Vascular Biology and Molecular Pathology, Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan) ,  Podyma-Inoue Katarzyna A. (Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan) ,  Hida Kyoko (Department of Vascular Biology and Molecular Pathology, Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan) ,  Miyazono Kohei (Department of Molecular Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Watabe Tetsuro (Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan)
Material： Cancer Science (Web)  (Cancer Sci (Web))
Volume： 111  Issue： 7  Page： 2385-2399  Publication year： 2020 
JST Material Number： U0505A  ISSN： 1349-7006  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： tumor cell ,...
Semi thesaurus term： ALK5 ,...

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Author keywords (7)： activin ,  endothelial-to-mesenchymal transition ,  epithelial-to-mesenchymal transition ,  integrin αv ,  TGF-β ,  TGF-β type I receptor (ALK5) ,  TNF-α

JST classification (2)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Tumor immunity  (ED03040A)

Terms in the title (7)： TNF-α ,  TGF-β ,  シグナル ,  増強 ,  誘導 ,  内皮間葉転換 ,  促進