Art
J-GLOBAL ID：202002244072911863   Reference number：20A0772146

Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors

Jag1は膵臓前駆体の成長と運命を協調させるために振動性DLL1-Notch-Hes1シグナル伝達モジュールを調節する【JST・京大機械翻訳】
Author (10)：
Seymour Philip Allan

About Seymour Philip Allan

(Novo Nordisk Foundation Center for Stem Cell Biology (DanStem), University of Copenhagen, Copenhagen N 2200, Denmark)

About Novo Nordisk Foundation Center for Stem Cell Biology (DanStem), University of Copenhagen, Copenhagen N 2200, Denmark

, 
Collin Caitlin Alexis

About Collin Caitlin Alexis

(Novo Nordisk Foundation Center for Stem Cell Biology (DanStem), University of Copenhagen, Copenhagen N 2200, Denmark)

About Novo Nordisk Foundation Center for Stem Cell Biology (DanStem), University of Copenhagen, Copenhagen N 2200, Denmark

, 
Egeskov-Madsen Anuska la Rosa

About Egeskov-Madsen Anuska la Rosa

(Novo Nordisk Foundation Center for Stem Cell Biology (DanStem), University of Copenhagen, Copenhagen N 2200, Denmark)

About Novo Nordisk Foundation Center for Stem Cell Biology (DanStem), University of Copenhagen, Copenhagen N 2200, Denmark

, 
Jorgensen Mette Christine

About Jorgensen Mette Christine

(Novo Nordisk Foundation Center for Stem Cell Biology (DanStem), University of Copenhagen, Copenhagen N 2200, Denmark)

About Novo Nordisk Foundation Center for Stem Cell Biology (DanStem), University of Copenhagen, Copenhagen N 2200, Denmark

, 
Shimojo Hiromi

About Shimojo Hiromi

(Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan)

About Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan

, 
Imayoshi Itaru

About Imayoshi Itaru

(Research Center for Dynamic Living Systems, Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan)

About Research Center for Dynamic Living Systems, Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan

, 
de Lichtenberg Kristian Honnens

About de Lichtenberg Kristian Honnens

(Novo Nordisk Foundation Center for Stem Cell Biology (DanStem), University of Copenhagen, Copenhagen N 2200, Denmark)

About Novo Nordisk Foundation Center for Stem Cell Biology (DanStem), University of Copenhagen, Copenhagen N 2200, Denmark

, 
Kopan Raphael

About Kopan Raphael

(Division of Developmental Biology, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA)

About Division of Developmental Biology, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA

, 
Kageyama Ryoichiro

About Kageyama Ryoichiro

(Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan)

About Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan

, 
Serup Palle

About Serup Palle

(Novo Nordisk Foundation Center for Stem Cell Biology (DanStem), University of Copenhagen, Copenhagen N 2200, Denmark)

About Novo Nordisk Foundation Center for Stem Cell Biology (DanStem), University of Copenhagen, Copenhagen N 2200, Denmark


Material：
Developmental Cell  (Dev Cell)

About Developmental Cell


Volume： 52  Issue： 6  Page： 731-747.e8  Publication year： 2020 
JST Material Number： W1692A  ISSN： 1534-5807  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)
Abstract/Point：
Abstract/Point
Japanese summary of the article(about several hundred characters).
All summary is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
Notch signaling controls proli...
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Thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
effector

About effector

, 
versatility

About versatility

, 
*Notch receptor

About Notch receptor

, 
anatomy

About anatomy

, 
acinar cell

About acinar cell

, 
*precursor(substance)

About precursor(substance)

, 
*cellular signal transduction

About cellular signal transduction

, 
morphogenesis

About morphogenesis


Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
化生

About 化生

, 
特異性

About 特異性

, 
Dll1蛋白質

About Dll1蛋白質

, 
リガンド

About リガンド

, 
前駆細胞

About 前駆細胞

, 
Notchシグナリング

About Notchシグナリング

, 
*Hes1蛋白質

About Hes1蛋白質

, 【Automatic Indexing@JST】
Author keywords (9)：
Notch

About Notch

, 
oscillations

About oscillations

, 
cis-inhibition

About cis-inhibition

, 
pancreas

About pancreas

, 
development

About development

, 
fate

About fate

, 
Dll1

About Dll1

, 
Jag1

About Jag1

, 
Hes1

About Hes1

JST classification (2)：
JST classification
Category name(code) classified by JST.
Development(=generation)and differentiation 
(EJ16020W)

About Development(=generation)and differentiation

,  Cell physiology in general 
(EF02010S)

About Cell physiology in general

Terms in the title (11)：
Terms in the title
Keywords automatically extracted from the title.
膵臓

About 膵臓

, 
前駆体

About 前駆体

, 
成長

About 成長

, 
協調

About 協調

, 
振動性

About 振動性

, 
Dll1

About Dll1

, 
Notch

About Notch

, 
Hes1

About Hes1

, 
シグナル伝達

About シグナル伝達

, 
モジュール

About モジュール

, 
調節

About 調節


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