Art

J-GLOBAL ID：202002244746486351   Reference number：20A0649840

Drug recrystallization in drug-in-adhesive transdermal delivery system: A case study of deteriorating the mechanical and rheological characteristics of testosterone TDS

接着剤経皮デリバリーシステムにおける薬物再結晶化:テストステロンTDSの機械的およびレオロジー的特性の劣化の事例研究【JST・京大機械翻訳】

Author (10)： Mohamed Loqman A. (Division of Pharmaceutical Manufacturing II, Office of Pharmaceutical Manufacturing Assessment, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, Food and Drug Administration, Maryland, USA) ,  Kamal Nahid (Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, Food and Drug Administration, Maryland, USA) ,  Elfakhri Khaled H. (Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, Food and Drug Administration, Maryland, USA) ,  Willett Daniel (Division of Pharmaceutical Analysis, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, Food and Drug Administration, MO, USA) ,  Wokovich Anna (Division of Pharmaceutical Analysis, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, Food and Drug Administration, MO, USA) ,  Strasinger Caroline (Division of New Drug Products II, Office of New Drug Products, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, Food and Drug Administration, Maryland, USA) ,  Cruz Celia N. (Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, Food and Drug Administration, Maryland, USA) ,  Raney Sam G. (Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA) ,  Ashraf Muhammad (Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, Food and Drug Administration, Maryland, USA) ,  Zidan Ahmed S (Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, Food and Drug Administration, Maryland, USA)
Material： International Journal of Pharmaceutics  (Int J Pharm)
Volume： 578  Page： Null  Publication year： 2020 
JST Material Number： A0285B  ISSN： 0378-5173  CODEN： IJPHD  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： This study investigated the ef...

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Thesaurus term： shear strength ,  *crystallization ,  *recrystallization ,  polarizing microscope ,  visual sense ,  osmosis ,  *adhesion(bond) ,  *case study ,  in vitro experiment ,  drug release ,  human(primates) ,  *rheology ,  *crystal ,  *adhesive ,  viscoelasticity

Author keywords (6)： Adhesion ,  Crystallization ,  Drug release ,  Permeation ,  Testosterone ,  Transdermal delivery system

JST classification (3)： Basic biopharmacy  (GY01021U) ,  Medical materials  (GA05040H) ,  Pharmaceutical preparations in general  (GY02010Z)

Terms in the title (8)： 接着剤 ,  経皮デリバリー ,  薬物 ,  再結晶化 ,  テストステロン ,  TDS ,  レオロジー ,  研究