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J-GLOBAL ID：202002244820481116   Reference number：20A2342041

Construction of lactic acid-tolerant Saccharomyces cerevisiae by using CRISPR-Cas-mediated genome evolution for efficient d-lactic acid production

効率的d-乳酸生産のためのCRISPR-Cas仲介ゲノム進化を用いた乳酸耐性Saccharomyces cerevisiaeの構築【JST・京大機械翻訳】

Author (6)： Mitsui Ryosuke (Department of Chemical Engineering, Osaka Prefecture University, Osaka, Japan) ,  Yamada Ryosuke (Department of Chemical Engineering, Osaka Prefecture University, Osaka, Japan) ,  Matsumoto Takuya (Department of Chemical Engineering, Osaka Prefecture University, Osaka, Japan) ,  Yoshihara Shizue (Department of Biological Sciences, Osaka Prefecture University, Osaka, Japan) ,  Tokumoto Hayato (Department of Biological Sciences, Osaka Prefecture University, Osaka, Japan) ,  Ogino Hiroyasu (Department of Chemical Engineering, Osaka Prefecture University, Osaka, Japan)
Material： Applied Microbiology and Biotechnology  (Appl Microbiol Biotechnol)
Volume： 104  Issue： 21  Page： 9147-9158  Publication year： 2020 
JST Material Number： H0764A  ISSN： 0175-7598  CODEN： EJABDD  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Abstract: Lactic acid (LA) is ...

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Thesaurus term： gene ,  glycolysis ,  substrate(biochemistry) ,  yeast ,  fermentation ,  lactic acid bacteria ,  *Saccharomyces ,  *Saccharomyces cerevisiae ,  medical material ,  Leuconostoc mesenteroides ,  neutralization ,  polylactic acid ,  aliphatic alcohol ,  aliphatic carboxylic acid ,  secondary alcohol ,  hydroxy acid ,  hexose ,  aldose
Semi thesaurus term： バイオプラスチック , 【Automatic Indexing@JST】

Author keywords (5)： Saccharomyces cerevisiae ,  Lactic acid tolerance ,  Transcriptome analysis ,  d-Lactic acid production ,  Non-neutralized fermentation

JST classification (3)： Metabolism and nutrition  (EG03054K) ,  Microbial metabolite production  (FK03020A) ,  Gene manipulation  (EC02050B)

Substance index (2)： Lactic acid ,  Glucose

Terms in the title (9)： D-乳酸 ,  CRISPR ,  CAS ,  仲介 ,  ゲノム進化 ,  乳 ,  酸耐性 ,  Saccharomyces ,  構築