Art

J-GLOBAL ID：202002244964802524   Reference number：20A1086810

Impact of degree of supersaturation on the dissolution and oral absorption behaviors of griseofulvin amorphous solid dispersions

グリセオフルビン非晶質固体分散の溶解と経口吸収挙動に及ぼす過飽和度の影響

Author (7)： Kawakami Kohsaku (International Center for Materials Nanoarchitectonics, National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki, 305-0044, Japan) ,  Suzuki Kyosuke (Pharmaceutical and ADMET Research Department, Daiichi Sankyo RD Novare Co., Ltd., 1-16-13, Kitakasai, Edogawa-ku, Tokyo, Japan) ,  Fukiage Masafumi (Pharmaceutical R&D, Ono Pharmaceutical Co., Ltd., 3-3-1, Sakurai, Shimamoto-cho, Mishima-gun, Osaka, 618-8585, Japan) ,  Matsuda Maki (Research & Development Division, Towa Pharmaceutical Co., Ltd., 134, Chudoji Minami-machi, Shimogyo-ku, Kyoto, 600-8813, Japan) ,  Nishida Yohei (Technology Research & Development, Sumitomo Dainippon Pharma Co., Ltd., 33-94, Enoki-cho, Suita, Osaka, 564-0053, Japan) ,  Oikawa Michinori (Pharmaceutical Development Department, Sawai Pharmaceutical Co., Ltd., 5-2-30, Miyahara, Yodogawa-ku, Osaka, 532-0003, Japan) ,  Fujita Takuya (College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-Higashi, Kusatsu, Shiga, 525-8577, Japan)
Material： Journal of Drug Delivery Science and Technology  (J Drug Deliv Sci Technol)
Volume： 56  Issue： PB  Page： Null  Publication year： Apr. 2020 
JST Material Number： W2117A  ISSN： 1773-2247  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： amorphous state ,...
Semi thesaurus term： Eudragit

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Author keywords (6)： Solid dispersion ,  Supersaturation ,  Liquid-liquid phase separation ,  Oral absorption ,  Dissolution test ,  In vitro-in vivo correlation

JST classification (2)： Basic biopharmacy  (GY01021U) ,  Basic research of antifungal drugs  (GW17060K)

Substance index (1)： Griseofulvin

Terms in the title (5)： グリセオフルビン ,  溶解 ,  経口吸収 ,  挙動 ,  過飽和度