Art

J-GLOBAL ID：202002245252521522   Reference number：20A1163151

Comparison of the inducibility of CYP mRNA exposed to typical inducers in fresh and cryopreserved cynomolgus monkey hepatocytes

新鮮および凍結保存カニクイザル肝細胞における典型的誘導剤に曝露されたCYP mRNAの誘導性の比較

Author (11)： Koeda Akiko (Ina Research Inc., Ina, Japan) ,  Koeda Akiko (Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan) ,  Iwao Takahiro (Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan) ,  Iwao Takahiro (Educational Research Center for Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan) ,  Nakanishi Anna (Educational Research Center for Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan) ,  Mizuno Shota (Educational Research Center for Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan) ,  Yamashita Misaki (Educational Research Center for Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan) ,  Sakai Yoko (Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan) ,  Nakamura Katsunori (Department of Pharmacy, Ryukyu University Hospital, Okinawa, Japan) ,  Matsunaga Tamihide (Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan) ,  Matsunaga Tamihide (Educational Research Center for Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan)
Material： Drug Metabolism and Pharmacokinetics (Web)  (Drug Metab Pharmacokinet (Web))
Volume： 35  Issue： 3  Page： 304-312  Publication year： 2020 
JST Material Number： U0705A  ISSN： 1347-4367  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *enzyme induction ,...
Semi thesaurus term： *Cytochrome P-450 Enzyme Inducers ,...

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Author keywords (7)： Cynomolgus monkey hepatocyte ,  Monolayer ,  Co-culture ,  Spheroid ,  Induction ,  Cytochrome P450 ,  Nuclear receptor

JST classification (1)： Basic biopharmacy  (GY01021U)

Substance index (3)： Omeprazole ,  Rifampin ,  Phenobarbital

Terms in the title (7)： 凍結保存 ,  カニクイザル ,  肝細胞 ,  誘導 ,  曝露 ,  CYP ,  mRNA