Art

J-GLOBAL ID：202002246285308049   Reference number：20A2762956

Imbalance in glycemic control between the treatment and placebo groups in cardiovascular outcome trials in type 2 diabetes

2型糖尿病における心血管転帰試験における治療とプラセボ群間の血糖コントロールの不均衡【JST・京大機械翻訳】

Author (2)： Shimazawa Rumiko (Department of Clinical Pharmacology, Tokai University School of Medicine, Isehara, Japan) ,  Ikeda Masayuki (Department of Medical Informatics, Kagawa University Hospital, Miki-cho, Japan)
Material： Journal of Pharmaceutical Policy and Practice (Web)
Volume： 12  Issue： 1  Page： 1-8  Publication year： 2019 
JST Material Number： U7263A  ISSN： 2052-3211  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Glycated hemoglobin (HbA1c) is...

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Thesaurus term： *placebo ,  *blood glucose ,  hypoglycemic drug ,  Food and Drug Administration ,  double blind test ,  cardiovascular disease ,  *cardiovascular system ,  hypoglycemia ,  effectiveness ,  *type 2 diabetes mellitus ,  HbA1c
Semi thesaurus term： *血糖コントロール ,  心血管リスク ,  血糖コントロール不良 ,  非劣性試験 , 【Automatic Indexing@JST】

Author keywords (7)： Bias ,  Cardiovascular diseases ,  Clinical trials ,  Drug approval ,  Glycated hemoglobin ,  Hypoglycemic agents ,  Type 2 diabetes mellitus

JST classification (2)： Clinical application of drugs acting on carbohydrate metabolism  (GW13030B) ,  Treatment for metabolic diseases,nutritional diseases.  (GD05030F)

Reference (49)：

• Diabetes Care; Translating the A1C assay into estimated average glucose values; DM Nathan, J Kuenen, R Borg, H Zheng, D Schoenfeld, RJ Heine; 31; 2008; 1473-1478; 10.2337/dc08-0545; citation_id=CR1
• Lancet; Effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus: a meta-analysis of randomised controlled trials; KK Ray, SR Seshasai, S Wijesuriya; 373; 2009; 1765-1772; 10.1016/S0140-6736(09)60697-8; citation_id=CR2
• Lancet; Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34); ; 352; 1998; 854-865; 10.1016/S0140-6736(98)07037-8; citation_id=CR3
• USFDA. FDA Background Document. Endocrinologic and Metabolic Drugs Advisory Committee Meeting October 24-25, 2018.https://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/Drugs/EndocrinologicandMetabolicDrugsAdvisoryCommittee/UCM623913.pdf. Accessed 27 July 2019.
• JAMA; Effect of muraglitazar on death and major adverse cardiovascular events in patients with type 2 diabetes mellitus; SE Nissen, K Wolski, EJ Topol; 294; 2005; 2581-2586; 10.1001/jama.294.20.joc50147; citation_id=CR5

Terms in the title (8)： 2型糖尿病 ,  心血管 ,  転帰 ,  試験 ,  治療 ,  プラセボ ,  血糖コントロール ,  均衡