Art

J-GLOBAL ID：202002246606010751   Reference number：20A0026862

Highly versatile cancer photoimmunotherapy using photosensitizer-conjugated avidin and biotin-conjugated targeting antibodies

光増感剤共役アビジンおよびビオチン抱合標的抗体を用いた高度に多用途な癌光免疫療法【JST・京大機械翻訳】

Author (5)： Shirasu Naoto (Department of Biochemistry, Faculty of Medicine, Fukuoka University, Fukuoka, Japan) ,  Shibaguchi Hirotomo (Department of Biochemistry, Faculty of Medicine, Fukuoka University, Fukuoka, Japan) ,  Yamada Hiromi (Department of Biochemistry, Faculty of Medicine, Fukuoka University, Fukuoka, Japan) ,  Kuroki Masahide (Department of Biochemistry, Faculty of Medicine, Fukuoka University, Fukuoka, Japan) ,  Yasunaga Shin'ichiro (Department of Biochemistry, Faculty of Medicine, Fukuoka University, Fukuoka, Japan)
Material： Cancer Cell International (Web)
Volume： 19  Issue： 1  Page： 1-13  Publication year： 2019 
JST Material Number： U7315A  ISSN： 1475-2867  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Photoimmunotherapy (PIT) emplo...

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Thesaurus term： flow cytometry ,  *conjugation ,  biotinylation ,  *antibody ,  *Immunotherapy ,  near infrared radiation ,  *conjugation (metabolism) ,  tumorigenesis ,  *Avidin ,  MCF7 cell ,  complex (substance) ,  tumor ,  *photosensitizer ,  targeting ,  clone ,  *albumin ,  *glycoprotein ,  *egg protein

Author keywords (5)： Avidin ,  Biotinylated antibody ,  Cancer stem cell ,  Tumor microenvironment ,  Photoimmunotherapy

JST classification (2)： Gene expression  (EC02040Q) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Reference (32)：

• Acc Chem Res; Near-infrared photoimmunotherapy of cancer; H Kobayashi, PL Choyke; 52; 8; 2019; 2332-2339; 10.1021/acs.accounts.9b00273; citation_id=CR1
• Bioconjug Chem; Near-infrared photoimmunotherapy: photoactivatable antibody-drug conjugates (ADCs); H Kobayashi, GL Griffiths, PL Choyke; 2019; 10.1021/acs.bioconjchem.9b00546; citation_id=CR2
• Nat Med; Cancer cell-selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules; M Mitsunaga, M Ogawa, N Kosaka, LT Rosenblum, PL Choyke, H Kobayashi; 17; 12; 2011; 1685-1691; 10.1038/nm.2554; citation_id=CR3
• ACS Cent Sci; Photoinduced ligand release from a silicon phthalocyanine dye conjugated with monoclonal antibodies: a mechanism of cancer cell cytotoxicity after near-infrared photoimmunotherapy; K Sato, K Ando, S Okuyama, S Moriguchi, T Ogura, S Totoki; 4; 11; 2018; 1559-1569; 10.1021/acscentsci.8b00565; citation_id=CR4
• Int J Cancer; Potent and specific antitumor effect of CEA-targeted photoimmunotherapy; N Shirasu, H Yamada, H Shibaguchi, M Kuroki, M Kuroki; 135; 11; 2014; 2697-2710; 10.1002/ijc.28907; citation_id=CR5

Terms in the title (10)： 光増感剤 ,  共役 ,  アビジン ,  ビオチン ,  抱合 ,  標的 ,  抗体 ,  用途 ,  癌 ,  光免疫療法