Art

J-GLOBAL ID：202002246783396145   Reference number：20A0430231

Plasma Lipidomic Analyses in Cohorts With mTBI and/or PTSD Reveal Lipids Differentially Associated With Diagnosis and APOE ε4 Carrier Status

MTBIおよび/またはPTSDとのコホートにおける血漿リピドミクス分析は,診断およびAPOE ε4キャリア状態と示差的に関連する脂質を明らかにする【JST・京大機械翻訳】

Author (29)： Huguenard Claire J. C. (The Roskamp Institute, Sarasota, FL, United States) ,  Huguenard Claire J. C. (School of Life, Health and Chemical Sciences, The Open University, Milton Keynes, United Kingdom) ,  Huguenard Claire J. C. (James A. Haley Veterans’ Hospital, Tampa, FL, United States) ,  Cseresznye Adam (The Roskamp Institute, Sarasota, FL, United States) ,  Cseresznye Adam (James A. Haley Veterans’ Hospital, Tampa, FL, United States) ,  Evans James E. (The Roskamp Institute, Sarasota, FL, United States) ,  Evans James E. (James A. Haley Veterans’ Hospital, Tampa, FL, United States) ,  Oberlin Sarah (The Roskamp Institute, Sarasota, FL, United States) ,  Oberlin Sarah (James A. Haley Veterans’ Hospital, Tampa, FL, United States) ,  Langlois Heather (The Roskamp Institute, Sarasota, FL, United States) ,  Langlois Heather (James A. Haley Veterans’ Hospital, Tampa, FL, United States) ,  Ferguson Scott (The Roskamp Institute, Sarasota, FL, United States) ,  Ferguson Scott (School of Life, Health and Chemical Sciences, The Open University, Milton Keynes, United Kingdom) ,  Ferguson Scott (James A. Haley Veterans’ Hospital, Tampa, FL, United States) ,  Darcey Teresa (The Roskamp Institute, Sarasota, FL, United States) ,  Darcey Teresa (James A. Haley Veterans’ Hospital, Tampa, FL, United States) ,  Nkiliza Aurore (The Roskamp Institute, Sarasota, FL, United States) ,  Nkiliza Aurore (James A. Haley Veterans’ Hospital, Tampa, FL, United States) ,  Dretsch Michael (US Army Medical Research Directorate-West, Walter Reed Army Institute of Research, Joint Base Lewis-McChord, Tacoma, WA, United States) ,  Dretsch Michael (U.S. Army Aeromedical Research Laboratory, Fort Rucker, AL, United States) ,  Mullan Michael (The Roskamp Institute, Sarasota, FL, United States) ,  Mullan Michael (School of Life, Health and Chemical Sciences, The Open University, Milton Keynes, United Kingdom) ,  Mullan Michael (James A. Haley Veterans’ Hospital, Tampa, FL, United States) ,  Crawford Fiona (The Roskamp Institute, Sarasota, FL, United States) ,  Crawford Fiona (School of Life, Health and Chemical Sciences, The Open University, Milton Keynes, United Kingdom) ,  Crawford Fiona (James A. Haley Veterans’ Hospital, Tampa, FL, United States) ,  Abdullah Laila (The Roskamp Institute, Sarasota, FL, United States) ,  Abdullah Laila (School of Life, Health and Chemical Sciences, The Open University, Milton Keynes, United Kingdom) ,  Abdullah Laila (James A. Haley Veterans’ Hospital, Tampa, FL, United States)
Material： Frontiers in Physiology (Web)
Volume： 11  Page： 12  Publication year： 2020 
JST Material Number： U7093A  ISSN： 1664-042X  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： The differential diagnosis bet...

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Thesaurus term： *population (statistics) ,  *lipid ,  saturation ratio ,  *apo E ,  stratification ,  sequela ,  allele ,  phosphatidylserine ,  mass spectrometry ,  interaction ,  *Plasma ,  cerebral infarction ,  differential diagnosis ,  biomarker ,  long chain ,  Disease ,  cerebrovascular disorder

Author keywords (6)： traumatic brain injury ,  post-traumatic stress disorder ,  biomarkers ,  lipids ,  apolipoprotein ε4 ,  mass spectrometry

JST classification (2)： Metabolism and nutrition of lipids  (EJ02034Q) ,  Metabolic diseases,nutritional diseases in general.  (GD05010J)

Reference (89)：

• Abdullah L., Evans J., Ferguson S., Mouzon B., Montague H., Reed J., et al (2014). Lipidomic analyses identify injury-specific phospholipid changes 3 mo after traumatic brain injury. FASEB J. 28 5311-5321. doi: 10.1096/fj.14-258228
• Adibhatla R., Hatcher J. (2007). Role of lipids in brain injury and diseases. Future Lipidol. 2 403-422. doi: 10.2217/17460875.2.4.403
• Adrian H., Marten K., Salla N., Lasse V. (2016). Biomarkers of traumatic brain injury: temporal changes in body fluids. eNeuro 3:ENEURO.0294-16.2016. doi: 10.2217/17460875.2.4.403
• Ahmadian A., Neylan T., Metzler T., Cohen B. (2019). Longitudinal association of PTSD symptoms and self-reported physical functioning among Veterans. J. Affect. Disord. 250 1-8. doi: 10.1016/j.jad.2019.02.048
• American Psychiatric Association (2013). Diagnostic and Statistical Manual of Mental Disorders, 5th Edn, Virginia: American Psychiatric Association. doi: 10.1016/j.jad.2019.02.048

Terms in the title (9)： PTSD ,  コホート ,  血漿 ,  リピドミクス ,  分析 ,  診断 ,  APOE ,  キャリア状態 ,  脂質