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J-GLOBAL ID：202002246818385214   Reference number：20A0498525

Surface Dependent Dual Recognition of a G-quadruplex DNA With Neomycin-Intercalator Conjugates

ネオマイシン-インターカレータ複合体によるG-四重鎖DNAの表面依存性二重認識【JST・京大機械翻訳】

Author (6)： Ranjan Nihar (Laboratory for Medicinal Chemistry, Department of Chemistry, Clemson University, Clemson, SC, United States) ,  Ranjan Nihar (Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Raebareli, India) ,  Andreasen Katrine F. (Laboratory for Medicinal Chemistry, Department of Chemistry, Clemson University, Clemson, SC, United States) ,  Arora Yashaswina (Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Raebareli, India) ,  Xue Liang (Laboratory for Medicinal Chemistry, Department of Chemistry, Clemson University, Clemson, SC, United States) ,  Arya Dev P. (Laboratory for Medicinal Chemistry, Department of Chemistry, Clemson University, Clemson, SC, United States)
Material： Frontiers in Chemistry (Web)
Volume： 8  Page： 60  Publication year： 2020 
JST Material Number： U7065A  ISSN： 2296-2646  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： G-quadruplexes have been chara...

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Thesaurus term： interaction ,  bacterium ,  heat denaturation ,  affinity ,  *DNA ,  quadruplex ,  binding site ,  double bond ,  rRNA ,  circular dichroism ,  HIV ,  malaria ,  stoichiometry ,  *heavy chain ,  *complex(substance)

Author keywords (5)： G-quadruplex ,  Oxytricha Nova ,  neomycin ,  DNA ,  FID

JST classification (2)： Gene expression  (EC02040Q) ,  Plant physiology in general  (EH02010Y)

Reference (56)：

• Artusi S., Nadai M., Perrone R., Biasolo M. A., Palu G., Flamand L., et al. (2015). The herpes simplex virus-1 genome contains multiple clusters of repeated G-quadruplex: implications for the antiviral activity of a G-quadruplex ligand. Antiviral Res. 118, 123-131. doi: 10.1016/j.antiviral.2015.03.016
• Arya D. P. (2007). Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery. Hoboken, NJ: John Wiley & Sons. doi: 10.1002/9780470149676
• Arya D. P., Coffee R. L., Willis B., Abramovitch A. I. (2001). Aminoglycoside- nucleic acid interactions: remarkable stabilization of DNA and RNA triple helices by neomycin. J. Am. Chem. Soc. 123, 5385-5395. doi: 10.1021/ja003052x
• Arya D. P., Xue L., Tennant P. (2003). Combining the best in triplex recognition: synthesis and nucleic acid binding of a BQQ- neomycin conjugate. J. Am. Chem. Soc. 125, 8070-8071. doi: 10.1021/ja034241t
• Balagurumoorthy P., Brahmachari S. K. (1994). Structure and stability of human telomeric sequence. J. Biol. Chem. 269, 21858-22169. doi: 10.1021/ja034241t

Terms in the title (6)： ネオマイシン ,  インターカレータ ,  複合体 ,  G-四重鎖 ,  DNA ,  依存性