Art

J-GLOBAL ID：202002247248646958   Reference number：20A1621854

Local Necrotic Cells Trigger Systemic Immune Activation via Gut Microbiome Dysbiosis in Drosophila

局所的壊死性細胞はDrosophilaにおける腸内マイクロバイオームジストビオーシスを介して全身免疫活性化を誘発する【JST・京大機械翻訳】

Author (14)： Kosakamoto Hina (Department of Genetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan) ,  Yamauchi Toshitaka (Department of Genetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan) ,  Akuzawa-Tokita Yoriko (Department of Genetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan) ,  Nishimura Kei (Department of Genetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan) ,  Soga Tomoyoshi (Institute for Biosciences, Keio University, Tsuruoka, Yamagata 997-0052, Japan) ,  Murakami Takumi (Department of Informatics, National Institute of Genetics, Mishima, Shizuoka 411-8540, Japan) ,  Mori Hiroshi (Department of Informatics, National Institute of Genetics, Mishima, Shizuoka 411-8540, Japan) ,  Yamamoto Kyosuke (Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki 305-8566, Japan) ,  Miyazaki Ryo (Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki 305-8566, Japan) ,  Miyazaki Ryo (Computational Bio Big Data Open Innovation Laboratory (CBBD-OIL), AIST, Tokyo 169-8555, Japan) ,  Koto Akiko (Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki 305-8566, Japan) ,  Koto Akiko (Computational Bio Big Data Open Innovation Laboratory (CBBD-OIL), AIST, Tokyo 169-8555, Japan) ,  Miura Masayuki (Department of Genetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan) ,  Obata Fumiaki (Department of Genetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan)
Material： Cell Reports
Volume： 32  Issue： 3  Page： Null  Publication year： 2020 
JST Material Number： W3124A  ISSN： 2211-1247  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Necrotic cells elicit an infla...

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Thesaurus term： interaction ,  *necrosis ,  inflammation ,  immunological reaction ,  *reproductive cell ,  microflora ,  *Drosophila ,  Gluconobacter ,  cellular signal transduction ,  apoptosis ,  natural immunity
Semi thesaurus term： メタボローム ,  常在菌叢ゲノム ,  炎症反応 ,  *免疫活性化 , 【Automatic Indexing@JST】

Author keywords (8)： Immune response ,  gut microbiota ,  necrosis ,  apoptosis ,  lifespan ,  metabolome ,  gluconobacter ,  Drosophila

JST classification (4)： Intestines  (EJ06040N) ,  Digestive system diseases  (GH03000W) ,  Immunological reaction in general  (ED03010T) ,  Infectious immunity  (ED03030P)

Terms in the title (7)： 壊死 ,  性細胞 ,  Drosophila ,  腸 ,  全身 ,  免疫活性化 ,  誘発