Art

J-GLOBAL ID：202002247530809498   Reference number：20A0525461

In vitro profiling of opioid ligands using the cAMP formation inhibition assay and the β-arrestin2 recruitment assay: No two ligands have the same profile

cAMP形成阻害アッセイとβ-アレスチン2動員アッセイを用いたオピオイド配位子のin vitroプロファイリング:2つのリガンドは同じプロファイルを持たない【JST・京大機械翻訳】

Author (9)： Kuo Andy (School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia) ,  Magiera Julia (School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia) ,  Rethwan Nursyazwani (School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia) ,  Andersson .ANGS.sa (Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia) ,  Leen Lam Ai (School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia) ,  Wyse Bruce (Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia) ,  Meutermans Wim (VAST Bioscience Pty Ltd, Toowong, Brisbane, QLD, Australia) ,  Lewis Richard (Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia) ,  Smith Maree (School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia)
Material： European Journal of Pharmacology  (Eur J Pharmacol)
Volume： 872  Page： Null  Publication year： 2020 
JST Material Number： B0841A  ISSN： 0014-2999  CODEN： EJPHAZ  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Previously, we showed that no ...

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Thesaurus term： antinociceptive action ,  rat ,  *narcotic analgesic ,  effectiveness ,  receptor ,  HEK293 cell ,  *in vitro experiment ,  opiate receptor ,  fatty acid ,  nitrogen heterocyclic compound ,  aromatic amine ,  carboxamide ,  ether ,  alicyclic compound ,  central nervous system drug ,  phenolic compound ,  oxygen heterocyclic compound ,  bridged compound ,  morphinan alkaloid ,  polynuclear aromatic compound ,  diol ,  phenol ether ,  hydroxy ketone ,  ketone ,  vinyl compound ,  hydroxy compound ,  tricyclic diterpene ,  carboxylate(ester) ,  adenine nucleotide ,  ribonucleotide ,  cyclic nucleotide
Semi thesaurus term： アゴニスト ,  *βアレスチン2 , 【Automatic Indexing@JST】

Author keywords (6)： Beta arrestin ,  cAMP ,  MOP ,  DOP ,  KOP ,  Morphine

JST classification (1)： Basic research of psychotropic drugs  (GW03100Y)

Substance index (5)： Fentanyl ,  Buprenorphine ,  Oxycodone ,  Forskolin ,  cAMP

Terms in the title (9)： cAMP ,  阻害 ,  アッセイ ,  β-アレスチン2 ,  オピオイド ,  配位子 ,  プロファイリング ,  リガンド ,  プロファイル