Art

J-GLOBAL ID：202002249076968792   Reference number：20A0653965

Quantitative evaluation of the intratumoral distribution of platinum in oxaliplatin-treated rectal cancer: In situ visualization of platinum via synchrotron radiation X-ray fluorescence spectrometry

オキサリプラチン治療直腸癌における白金の腫瘍内分布の定量的評価:シンクロトロン放射蛍光X線分析による白金のin situ可視化【JST・京大機械翻訳】

Author (14)： Koba Ryo (Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Fujita Hayato (Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Nishibori Maiko (Faculty of Engineering Sciences, Kyushu University, Fukuoka, Japan) ,  Saeki Kiyoshi (Department of Anatomical Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Nagayoshi Kinuko (Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Sadakari Yoshihiko (Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Nagai Shuntaro (Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Sekizawa Oki (Japan Synchrotron Radiation Research Institute (JASRI), Hyogo, Japan) ,  Nitta Kiyofumi (Japan Synchrotron Radiation Research Institute (JASRI), Hyogo, Japan) ,  Manabe Tatsuya (Department of Surgery, Faculty of Medicine, Saga University, Saga, Japan) ,  Ueki Takashi (Department of Surgery, Hamanomachi Hospital, Fukuoka, Japan) ,  Ishida Tatsuhiro (Department of Pharmacokinetics and Biopharmaceutics, Institute of Biomedical Sciences, Tokushima University, Tokushima, Japan) ,  Oda Yoshinao (Department of Anatomical Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Nakamura Masafumi (Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan)
Material： International Journal of Cancer  (IJC)
Volume： 146  Issue： 9  Page： 2498-2509  Publication year： 2020 
JST Material Number： A0267B  ISSN： 0020-7136  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Oxaliplatin (l-OHP), a platinu...

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Thesaurus term： epithelium ,  *X-ray fluorescence analysis ,  Multivariate Analysis ,  drug therapy ,  detection limit ,  Drug Resistance ,  human ,  *visualization ,  *Platinum ,  calibration curve ,  trace element ,  *tumor ,  interstitial tissue ,  *rectal neoplasm ,  *synchrotron radiation ,  membrane and film ,  histomembrane

Author keywords (4)： rectal cancer ,  oxaliplatin ,  drug distribution ,  SR-XRF

JST classification (2)： Clinical application of antitumor(=antineoplastic)drugs  (GW16020L) ,  Analysis of drugs  (GV01040Q)

Terms in the title (10)： オキサリプラチン ,  治療 ,  直腸癌 ,  白金 ,  腫瘍 ,  分布 ,  定量的評価 ,  シンクロトロン放射 ,  蛍光X線分析 ,  可視化