Art

J-GLOBAL ID：202002249265896038   Reference number：20A0542153

Arsenic trioxide and curcumin attenuate cisplatin-induced renal fibrosis in rats through targeting Hedgehog signaling

三酸化ヒ素とクルクミンは,Hedgehogシグナル伝達を標的とすることによりラットにおけるシスプラチン誘発腎線維症を減弱する【JST・京大機械翻訳】

Author (5)： Maghmomeh Abdalkareem Omar (Department of Biochemistry, Faculty of Pharmacy, University of Mansoura, Mansoura, Egypt) ,  Maghmomeh Abdalkareem Omar (Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Mansoura, Egypt) ,  El-Gayar Amal Mohamed (Department of Biochemistry, Faculty of Pharmacy, University of Mansoura, Mansoura, Egypt) ,  El-Karef Amro (Department of Pathology, Faculty of Medicine, University of Mansoura, Mansoura, Egypt) ,  Abdel-Rahman Noha (Department of Biochemistry, Faculty of Pharmacy, University of Mansoura, Mansoura, Egypt)
Material： Naunyn-Schmiedeberg's Archives of Pharmacology
Volume： 393  Issue： 3  Page： 303-313  Publication year： 2020 
JST Material Number： D0140A  ISSN： 0028-1298  CODEN： NSAPCC  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Abstract: Renal fibrosis is a ...

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Thesaurus term： renal insufficiency ,  *cisplatin ,  desert ,  TGF beta ,  *fibrous disease ,  mRNA ,  repressor ,  chronic kidney disease ,  renal toxicity ,  smoothing ,  creatinine clearance ,  antitumor drug ,  *rat ,  urea nitrogen ,  kidney disease

Author keywords (5)： Kidney fibrosis ,  Hedgehog pathway ,  TGF-β1 ,  Arsenic trioxide ,  Curcumin

JST classification (3)： Basic research of drugs acting on urinary system  (GW11010R) ,  Basic medicine on urogenital system  (GM01020T) ,  Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W)

Terms in the title (9)： 三酸化ヒ素 ,  クルクミン ,  Hedgehogシグナル ,  標的 ,  ラット ,  シスプラチン ,  誘発 ,  腎線維症 ,  減弱