Art

J-GLOBAL ID：202002249528982428   Reference number：20A0527665

Safety, efficacy, and pharmacokinetics of pradefovir for the treatment of chronic hepatitis B infection

慢性B型肝炎感染の治療のためのプラデホビルの安全性,有効性および薬物動態【JST・京大機械翻訳】

Author (12)： Zhang Hong (Phase I Clinical Research Center, The First Hospital of Jilin University, Jilin, China) ,  Wu Min (Phase I Clinical Research Center, The First Hospital of Jilin University, Jilin, China) ,  Zhu Xiaoxue (Phase I Clinical Research Center, The First Hospital of Jilin University, Jilin, China) ,  Li Cuiyun (Phase I Clinical Research Center, The First Hospital of Jilin University, Jilin, China) ,  Li Xiaojiao (Phase I Clinical Research Center, The First Hospital of Jilin University, Jilin, China) ,  Jin Weili (Xi’an Xintong Pharmaceutical Research Co., Ltd, China) ,  Zhang Dengke (Xi’an Xintong Pharmaceutical Research Co., Ltd, China) ,  Chen Hong (Phase I Clinical Research Center, The First Hospital of Jilin University, Jilin, China) ,  Liu Chengjiao (Phase I Clinical Research Center, The First Hospital of Jilin University, Jilin, China) ,  Ding Yanhua (Phase I Clinical Research Center, The First Hospital of Jilin University, Jilin, China) ,  Niu Junqi (Department of Hepatology, The First Hospital of Jilin University, Jilin, China) ,  Liu Jingrui (Phase I Clinical Research Center, The First Hospital of Jilin University, Jilin, China)
Material： Antiviral Research  (Antivir Res)
Volume： 174  Page： Null  Publication year： 2020 
JST Material Number： D0654B  ISSN： 0166-3542  CODEN： ARSRDR  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Pradefovir is a liver targeted...

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Thesaurus term： viral infection ,  renal toxicity ,  antiviral action ,  hepatitis B virus ,  DNA ,  metabolite ,  clinical trial ,  HBe antigen ,  half-life ,  cholinesterase ,  *chronic hepatitis B ,  prodrug ,  serum ,  liver cirrhosis
Semi thesaurus term： 有害事象 , 【Automatic Indexing@JST】

Author keywords (5)： Prodrug ,  Pharmacokinetics ,  Safety ,  Viral hepatitis ,  Clinical trial

JST classification (1)： Basic research of antiviral drugs  (GW17040O)

Terms in the title (5)： 慢性B型肝炎 ,  感染 ,  治療 ,  安全性 ,  薬物動態