Art

J-GLOBAL ID：202002249961392531   Reference number：20A0457185

Down-regulation of RalGTPase-Activating Protein Promotes Colitis-Associated Cancer via NLRP3 Inflammasome Activation

RAGTPアーゼ活性化蛋白質のダウンレギュレーションはNLRP3インフラマソーム活性化を介して大腸炎関連癌を促進する【JST・京大機械翻訳】

Author (14)： Iida Tomoya (Department of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine, Sapporo, Japan) ,  Hirayama Daisuke (Department of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine, Sapporo, Japan) ,  Minami Naoki (Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Kyoto, Japan) ,  Matsuura Minoru (Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Kyoto, Japan) ,  Wagatsuma Kohei (Department of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine, Sapporo, Japan) ,  Kawakami Kentaro (Department of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine, Sapporo, Japan) ,  Nagaishi Kanna (Second Department of Anatomy, Sapporo Medical University School of Medicine, Sapporo, Japan) ,  Nojima Masanori (Center for Translational Research, The Institute of Medical Science Hospital, The University of Tokyo, Tokyo, Japan) ,  Ikeuchi Hiroki (Division of Lower Gastrointestinal, Department of Surgery, Hyogo College of Medicine, Nishinomiya, Japan) ,  Ikeuchi Hiroki (Inflammatory Bowel Disease Center, Hyogo College of Medicine, Nishinomiya, Japan) ,  Hirota Seiichi (Department of Surgical Pathology, Hyogo College of Medicine, Nishinomiya, Japan) ,  Shirakawa Ryutaro (Department of Molecular and Cellular Biology, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan) ,  Horiuchi Hisanori (Department of Molecular and Cellular Biology, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan) ,  Nakase Hiroshi (Department of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine, Sapporo, Japan)
Material： Cellular and Molecular Gastroenterology and Hepatology
Volume： 9  Issue： 2  Page： 277-293  Publication year： 2020 
JST Material Number： W3051A  ISSN： 2352-345X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Ral guanosine triphosphatase-a...

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Thesaurus term： *colitis(large intestine) ,  DNA microarray ,  *down-regulation ,  dextran sulfate ,  wild type ,  mucosa ,  subunit ,  colon ,  polymerase chain reaction ,  bone marrow ,  Ras protein ,  tumor ,  apoptosis ,  immersional wetting ,  matrix metalloproteinase

Author keywords (4)： Ral ,  Ral-GTPase Activating Protein (RalGAP) ,  Colitis-Associated Cancer ,  NLRP3 Inflammasome

JST classification (2)： Cell physiology in general  (EF02010S) ,  Tumors(=neoplasms)of digestive system  (GH04000D)

Terms in the title (6)： ダウンレギュレーション ,  NLRP3インフラマソーム ,  活性化 ,  大腸炎 ,  癌 ,  促進