Art

J-GLOBAL ID：202002250406644075   Reference number：20A0271399

The boundary lipid around DMPC-spanning influenza A M2 transmembrane domain channels: Its structure and potential for drug accommodation

DMPC-スパニングインフルエンザA M2膜貫通ドメインチャンネル周辺の境界脂質:その構造と薬物調節の可能性【JST・京大機械翻訳】

Author (14)： Konstantinidi Athina (Section of Pharmaceutical Chemistry, Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Athens 15771, Greece) ,  Chountoulesi Maria (Section of Pharmaceutical Technology, Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Athens 15771, Greece) ,  Naziris Nikolaos (Section of Pharmaceutical Technology, Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Athens 15771, Greece) ,  Sartori Barbara (Institute of Inorganic Chemistry, Graz University of Technology, Stremayrgasse 9/IV, A-8010 Graz, Austria) ,  Amenitsch Heinz (Institute of Inorganic Chemistry, Graz University of Technology, Stremayrgasse 9/IV, A-8010 Graz, Austria) ,  Mali Gregor (Department of Inorganic Chemistry and Technology, National Institute of Chemistry, Ljubljana SI-1001, Slovenia) ,  Cendak Tomaz (Department of Inorganic Chemistry and Technology, National Institute of Chemistry, Ljubljana SI-1001, Slovenia) ,  Plakantonaki Maria (Department of Chemistry, School of Natural Sciences, University of Patras, Rion, Patras 26500, Greece) ,  Triantafyllakou Iro (Department of Chemistry, School of Natural Sciences, University of Patras, Rion, Patras 26500, Greece) ,  Tselios Theodore (Department of Chemistry, School of Natural Sciences, University of Patras, Rion, Patras 26500, Greece) ,  Demetzos Costas (Section of Pharmaceutical Technology, Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Athens 15771, Greece) ,  Busath David D. (Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT 84602, USA) ,  Mavromoustakos Thomas (Section of Organic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Athens 15771, Greece) ,  Kolocouris Antonios (Section of Pharmaceutical Chemistry, Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Athens 15771, Greece)
Material： Biochimica et Biophysica Acta  (BBA. Biomembranes)
Volume： 1862  Issue： 3  Page： Null  Publication year： 2020 
JST Material Number： B0207A  ISSN： 0005-2728  CODEN： BBBMBS  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： We have investigated the pertu...

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Thesaurus term： channel ,  simulation ,  *influenza ,  *lipid ,  molecular dynamics ,  hydrophobic ,  ion ,  lipid bilayer membrane ,  small angle X-ray scattering ,  topology ,  interaction ,  bilayer ,  X-ray scattering ,  perturbation ,  alicyclic compound ,  bridged compound ,  primary amine

Author keywords (8)： Aminoadamantane derivatives ,  Boundary lipids ,  DMPC bilayers ,  DSC ,  Molecular dynamics ,  M2TM ,  Solid state NMR ,  X-ray scattering

JST classification (1)： Biomembrane in general  (EF04010G)

Substance index (1)： Amantadine

Terms in the title (9)： DMPC ,  膜貫通ドメイン ,  チャンネル ,  周辺 ,  境界 ,  脂質 ,  薬物 ,  調節 ,  可能性