Art

J-GLOBAL ID：202002250448064604   Reference number：20A0775727

Molecularly Engineered Macrophage-Derived Exosomes with Inflammation Tropism and Intrinsic Heme Biosynthesis for Atherosclerosis Treatment

アテローム性動脈硬化症治療のための炎症指向性および内因性ヘム生合成を伴う分子工学的マクロファージ由来エキソソーム【JST・京大機械翻訳】

Author (10)： Wu Guanghao (School of Life Science, Beijing Institute of Technology, No. 5 South Zhong Guan Cun Street, Beijing, 100081, China) ,  Zhang Jinfeng (School of Life Science, Beijing Institute of Technology, No. 5 South Zhong Guan Cun Street, Beijing, 100081, China) ,  Zhao Qianru (School of Life Science, Beijing Institute of Technology, No. 5 South Zhong Guan Cun Street, Beijing, 100081, China) ,  Zhuang Wanru (School of Life Science, Beijing Institute of Technology, No. 5 South Zhong Guan Cun Street, Beijing, 100081, China) ,  Ding Jingjing (School of Life Science, Beijing Institute of Technology, No. 5 South Zhong Guan Cun Street, Beijing, 100081, China) ,  Zhang Chi (School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637457, Singapore) ,  Gao Haijun (School of Life Science, Beijing Institute of Technology, No. 5 South Zhong Guan Cun Street, Beijing, 100081, China) ,  Pang Dai-Wen (Research Center for Analytical Sciences, College of Chemistry, Nankai University, No. 94 Weijin Road, Nankai District, Tianjin, 300071, China) ,  Pu Kanyi (School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637457, Singapore) ,  Xie Hai-Yan (School of Life Science, Beijing Institute of Technology, No. 5 South Zhong Guan Cun Street, Beijing, 100081, China)
Material： Angewandte Chemie. International Edition  (Angewandte Chemie. International Edition in English)
Volume： 59  Issue： 10  Page： 4068-4074  Publication year： 2020 
JST Material Number： H0127B  ISSN： 1433-7851  CODEN： ACIEAY  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Atherosclerosis (AS) is a majo...

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Thesaurus term： *Atherosclerosis ,  *macrophage ,  Chemokine Receptors ,  Electroporation ,  *Inflammation ,  image processing ,  *biosynthesis ,  Carbon Monoxide ,  anti-inflammatory action ,  cardiovascular disease ,  directionality ,  Membrane Proteins ,  *Exosomes ,  *endogenous ,  lactam ,  polyene ,  vinyl compound ,  dicarboxylic acid

Author keywords (4)： biosynthesis ,  exosomes ,  inflammation ,  membrane proteins

JST classification (2)： Basic biopharmacy  (GY01021U) ,  Basic research of anti-inflammatory drugs  (GW15010T)

Substance index (1)： Bilirubin

Terms in the title (8)： アテローム性動脈硬化症 ,  治療 ,  炎症 ,  内因性 ,  ヘム生合成 ,  分子工学 ,  マクロファージ ,  エキソソーム