Art

J-GLOBAL ID：202002252385924089   Reference number：20A0228309

CD4+ count-dependent concentration-effect relationship of rituximab in rheumatoid arthritis

関節リウマチにおけるリツキシマブのCD4+数依存性濃度効果相関【JST・京大機械翻訳】

Author (14)： Bensalem Amina (EA 7501 GICC, Universite de Tours, Tours, France) ,  Mulleman Denis (EA 7501 GICC, Universite de Tours, Tours, France) ,  Mulleman Denis (Department of Rheumatology, CHRU de Tours, Tours, France) ,  Thibault Gilles (EA 7501 GICC, Universite de Tours, Tours, France) ,  Thibault Gilles (Laboratory of Immunology, CHRU de Tours, Tours, France) ,  Thibault Gilles (ERL 7001, CNRS, Tours, France) ,  Azzopardi Nicolas (EA 7501 GICC, Universite de Tours, Tours, France) ,  Azzopardi Nicolas (ERL 7001, CNRS, Tours, France) ,  Goupille Philippe (EA 7501 GICC, Universite de Tours, Tours, France) ,  Goupille Philippe (Department of Rheumatology, CHRU de Tours, Tours, France) ,  Paintaud Gilles (EA 7501 GICC, Universite de Tours, Tours, France) ,  Paintaud Gilles (Department of Medical Pharmacology, CHRU de Tours, Tours, France) ,  Ternant David (EA 7501 GICC, Universite de Tours, Tours, France) ,  Ternant David (Department of Medical Pharmacology, CHRU de Tours, Tours, France)
Material： British Journal of Clinical Pharmacology  (BJCP)
Volume： 85  Issue： 12  Page： 2747-2758  Publication year： 2019 
JST Material Number： C0957B  ISSN： 0306-5251  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： AIMS: Rituximab is approved in...

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Thesaurus term： T cell ,  compartment model ,  biomarker ,  pharmacodynamics ,  mechanical model ,  *rheumatoid arthritis ,  half-life
Semi thesaurus term： DAS28 ,  *CD4陽性細胞 ,  *リツキシマブ , 【Automatic Indexing@JST】

Author keywords (5)： pharmacodynamics ,  pharmacokinetics ,  rheumatoid arthritis ,  rituximab ,  T-lymphocytes

JST classification (2)： Clinical biopharmacy  (GY01022L) ,  Clinical application of other drugs acting on central nervous system  (GW03130F)

Terms in the title (6)： 関節リウマチ ,  リツキシマブ ,  CD4+ ,  依存性 ,  濃度効果 ,  相関