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J-GLOBAL ID：202002253262380719   Reference number：20A1163149

Establishment of MDR1-knockout human induced pluripotent stem cell line

MDR1ノックアウトヒト人工多能性幹細胞株の確立

Author (14)： Negoro Ryosuke (Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, 565-0871, Japan) ,  Kawai Kanae (Laboratory of Biochemistry and Molecular Biology, School of Pharmaceutical Sciences, Osaka University, Osaka, 565-0871, Japan) ,  Ichikawa Moe (Laboratory of Biochemistry and Molecular Biology, School of Pharmaceutical Sciences, Osaka University, Osaka, 565-0871, Japan) ,  Deguchi Sayaka (Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, 565-0871, Japan) ,  Deguchi Sayaka (Laboratory of Hepatocyte Regulation, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, 567-0085, Japan) ,  Takayama Kazuo (Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, 565-0871, Japan) ,  Takayama Kazuo (Laboratory of Biochemistry and Molecular Biology, School of Pharmaceutical Sciences, Osaka University, Osaka, 565-0871, Japan) ,  Takayama Kazuo (Laboratory of Hepatocyte Regulation, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, 567-0085, Japan) ,  Takayama Kazuo (PRESTO, Japan Science and Technology Agency, Saitama, 332-0012, Japan) ,  Mizuguchi Hiroyuki (Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, 565-0871, Japan) ,  Mizuguchi Hiroyuki (Laboratory of Biochemistry and Molecular Biology, School of Pharmaceutical Sciences, Osaka University, Osaka, 565-0871, Japan) ,  Mizuguchi Hiroyuki (Laboratory of Hepatocyte Regulation, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, 567-0085, Japan) ,  Mizuguchi Hiroyuki (Global Center for Medical Engineering and Informatics, Osaka University, Osaka, 565-0871, Japan) ,  Mizuguchi Hiroyuki (Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives (OTRI), Osaka University, Osaka, 565-0871, Japan)
Material： Drug Metabolism and Pharmacokinetics (Web)  (Drug Metab Pharmacokinet (Web))
Volume： 35  Issue： 3  Page： 288-296  Publication year： 2020 
JST Material Number： U0705A  ISSN： 1347-4367  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *induced pluripotent stem cell ,...
Semi thesaurus term： Enterocytes ,...

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Author keywords (8)： iPS cell ,  ABCB1 ,  MDR1 ,  P-gp ,  CRISPR-Cas9 ,  Transporter ,  Genome editing ,  Hepatocytes

JST classification (2)： Basic biopharmacy  (GY01021U) ,  Cytology in general  (EF01000A)

Terms in the title (5)： MDR1 ,  ノックアウト ,  ヒト ,  人工多能性幹細胞 ,  株