Art

J-GLOBAL ID：202002253699319531   Reference number：20A0584587

Linc1557 is critical for the initiation of embryonic stem cell differentiation by directly targeting the LIF/STAT3 signaling pathway

LINC1557はLIF/STAT3シグナル伝達経路を直接標的化することにより胚幹細胞分化の開始に重要である【JST・京大機械翻訳】

Author (8)： Lan Yuanyuan (Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Collaborative Innovation Center for Brain Science, School of Life Sciences and Technology, Tongji University, Shanghai, People’s Republic ...) ,  Lu Chenqi (Department of Biostatistics and Computational Biology, State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, People’s Republic of China) ,  Yang Yiwei (Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Collaborative Innovation Center for Brain Science, School of Life Sciences and Technology, Tongji University, Shanghai, People’s Republic ...) ,  Liu Xiaoqin (Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Collaborative Innovation Center for Brain Science, School of Life Sciences and Technology, Tongji University, Shanghai, People’s Republic ...) ,  Guo Xudong (Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Collaborative Innovation Center for Brain Science, School of Life Sciences and Technology, Tongji University, Shanghai, People’s Republic ...) ,  Xi Jiajie (Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Collaborative Innovation Center for Brain Science, School of Life Sciences and Technology, Tongji University, Shanghai, People’s Republic ...) ,  Kang Jiuhong (Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Collaborative Innovation Center for Brain Science, School of Life Sciences and Technology, Tongji University, Shanghai, People’s Republic ...) ,  Wang Guiying (Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Collaborative Innovation Center for Brain Science, School of Life Sciences and Technology, Tongji University, Shanghai, People’s Republic ...)
Material： Stem Cells  (Stem Cells (Durham))
Volume： 38  Issue： 3  Page： 340-351  Publication year： 2020 
JST Material Number： A0655C  ISSN： 1066-5099  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Embryonic stem cells (ESCs) ha...

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Thesaurus term： phosphorylation ,  leukemia ,  *cellular signal transduction ,  *cell differentiation ,  mRNA ,  *ES cell ,  versatility ,  *targeting ,  transcriptome ,  *stem cell ,  *differentiation(biology) ,  repressor
Semi thesaurus term： 遺伝子ノックダウン法 ,  非翻訳長鎖RNA ,  *伝達経路 , 【Automatic Indexing@JST】

Author keywords (5)： differentiation initiation ,  embryonic stem cells ,  Linc1557 ,  mRNA stability ,  STAT3

JST classification (4)： Hematopoietic system  (EJ07020Y) ,  Cell physiology in general  (EF02010S) ,  Gene expression  (EC02040Q) ,  Development(=generation)and differentiation  (EJ16020W)

Terms in the title (6)： LIF ,  STAT3 ,  シグナル伝達経路 ,  標的化 ,  胚幹細胞 ,  分化