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J-GLOBAL ID：202002253699942269   Reference number：20A2284329

mTOR Mysteries: Nuances and Questions About the Mechanistic Target of Rapamycin in Neurodegeneration

mTOR mysteries:神経変性におけるラパマイシンの機構的標的に関する必要性と疑問【JST・京大機械翻訳】

Author (2)： Norwitz Nicholas G. (Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom) ,  Querfurth Henry (Department of Neurology, Tufts Medical Center, Boston, MA, United States)
Material： Frontiers in Neuroscience (Web)
Volume： 14  Page： 775  Publication year： 2020 
JST Material Number： U7087A  ISSN： 1662-453X  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： The mechanistic target of rapa...

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Thesaurus term： insulin ,  life style ,  targeting ,  Alzheimer disease ,  Parkinson's disease ,  *cellular signal transduction ,  protein complex ,  autophagy ,  ether ,  macrocyclic compound ,  lactam ,  lactone ,  enzyme inhibitor ,  hemiacetal ,  alicyclic alcohol ,  secondary alcohol ,  hydroxy ketone
Semi thesaurus term： 神経変性疾患 ,  *神経変性 ,  アゴニスト ,  調節因子 ,  mTORC1 ,  神経保護 , 【Automatic Indexing@JST】

Author keywords (6)： Alzheimer’s disease ,  antagonistic pleiotropy ,  autophagy ,  insulin/Akt ,  mTOR ,  Parkinson’s disease

JST classification (2)： Cell physiology in general  (EF02010S) ,  Basic neurology  (GN01020W)

Substance index (1)： Rapamycin

Reference (111)：

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Terms in the title (4)： mTOR ,  神経変性 ,  ラパマイシン ,  標的