Art

J-GLOBAL ID：202002254000545437   Reference number：20A2350723

Circulation of gut-preactivated naieve CD8⁺ T cells enhances antitumor immunity in B cell-defective mice

腸管活性化ナイーブCD8+T細胞の循環はB細胞欠損マウスにおける抗腫瘍免疫を増強する【JST・京大機械翻訳】

Author (11)： Akrami Maryam (Department of Immunology and Genomic Medicine, Kyoto University Graduate School of Medicine, 606-8501 Kyoto, Japan) ,  Menzies Rosemary (Department of Immunology and Genomic Medicine, Kyoto University Graduate School of Medicine, 606-8501 Kyoto, Japan) ,  Chamoto Kenji (Department of Immunology and Genomic Medicine, Kyoto University Graduate School of Medicine, 606-8501 Kyoto, Japan) ,  Miyajima Michio (Laboratory for Mucosal Immunity, Center for Integrative Medical Sciences, RIKEN Yokohama Institute, 230-0045 Yokohama, Japan) ,  Suzuki Ryuji (Repertoire Genesis Incorporation, 567-0085 Ibaraki, Japan) ,  Suzuki Ryuji (Department of Rheumatology and Clinical Immunology, National Hospital Organization Sagamihara Hospital, 252-0392 Sagamihara, Japan) ,  Sato Hiroyuki (Repertoire Genesis Incorporation, 567-0085 Ibaraki, Japan) ,  Nishii Akiko (Laboratory of Immunology, Faculty of Pharmacy, Osaka Ohtani University, 584-8540 Tondabayashi, Osaka, Japan) ,  Tomura Michio (Laboratory of Immunology, Faculty of Pharmacy, Osaka Ohtani University, 584-8540 Tondabayashi, Osaka, Japan) ,  Fagarasan Sidonia (Laboratory for Mucosal Immunity, Center for Integrative Medical Sciences, RIKEN Yokohama Institute, 230-0045 Yokohama, Japan) ,  Honjo Tasuku (Department of Immunology and Genomic Medicine, Kyoto University Graduate School of Medicine, 606-8501 Kyoto, Japan)
Material： Proceedings of the National Academy of Sciences of the United States of America  (PNAS)
Volume： 117  Issue： 38  Page： 23674-23683  Publication year： 2020 
JST Material Number： D0387A  ISSN： 0027-8424  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： The gut microbiome has garnere...

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Thesaurus term： microorganism ,  *tumor ,  mucosa ,  *T cell ,  function analysis ,  pathogen ,  stem cell ,  cellular signal transduction ,  up-regulation ,  *CD8 antigen ,  *tumor immunity
Semi thesaurus term： CD8陽性T細胞 ,  癌免疫療法 ,  単一細胞 ,  Sca-1蛋白質 , 【Automatic Indexing@JST】

Author keywords (5)： IgA ,  type I IFN signaling ,  circulation between gut and periphery ,  gut-microbiota education ,  mitochondrial activation

JST classification (1)： Immunological reaction in general  (ED03010T)

Terms in the title (9)： 腸管 ,  活性化 ,  CD8+T細胞 ,  循環 ,  B細胞 ,  欠損 ,  マウス ,  抗腫瘍免疫 ,  増強