Art
J-GLOBAL ID：202002255744929178   Reference number：20A0458037

Precise CRISPR/Cas9 editing of the NHE1 gene renders chickens resistant to the J subgroup of avian leukosis virus

NHE1遺伝子の正確なCRISPR/Cas9エディティングはトリ白血病ウイルスのJサブグループに耐性を示す【JST・京大機械翻訳】
Author (11)：
Koslova Anna

About Koslova Anna

(Institute of Molecular Genetics, Czech Academy of Sciences, 14220 Prague, Czech Republic)

About Institute of Molecular Genetics, Czech Academy of Sciences, 14220 Prague, Czech Republic

, 
Trefil Pavel

About Trefil Pavel

(BIOPHARM, Research Institute of Biopharmacy and Veterinary Drugs, 254 49 Jilove u Prahy, Czech Republic)

About BIOPHARM, Research Institute of Biopharmacy and Veterinary Drugs, 254 49 Jilove u Prahy, Czech Republic

, 
Mucksova Jitka

About Mucksova Jitka

(BIOPHARM, Research Institute of Biopharmacy and Veterinary Drugs, 254 49 Jilove u Prahy, Czech Republic)

About BIOPHARM, Research Institute of Biopharmacy and Veterinary Drugs, 254 49 Jilove u Prahy, Czech Republic

, 
Reinisova Marketa

About Reinisova Marketa

(Institute of Molecular Genetics, Czech Academy of Sciences, 14220 Prague, Czech Republic)

About Institute of Molecular Genetics, Czech Academy of Sciences, 14220 Prague, Czech Republic

, 
Plachy Jiri

About Plachy Jiri

(Institute of Molecular Genetics, Czech Academy of Sciences, 14220 Prague, Czech Republic)

About Institute of Molecular Genetics, Czech Academy of Sciences, 14220 Prague, Czech Republic

, 
Kalina Jiri

About Kalina Jiri

(BIOPHARM, Research Institute of Biopharmacy and Veterinary Drugs, 254 49 Jilove u Prahy, Czech Republic)

About BIOPHARM, Research Institute of Biopharmacy and Veterinary Drugs, 254 49 Jilove u Prahy, Czech Republic

, 
Kucerova Dana

About Kucerova Dana

(Institute of Molecular Genetics, Czech Academy of Sciences, 14220 Prague, Czech Republic)

About Institute of Molecular Genetics, Czech Academy of Sciences, 14220 Prague, Czech Republic

, 
Geryk Josef

About Geryk Josef

(Institute of Molecular Genetics, Czech Academy of Sciences, 14220 Prague, Czech Republic)

About Institute of Molecular Genetics, Czech Academy of Sciences, 14220 Prague, Czech Republic

, 
Krchlikova Veronika

About Krchlikova Veronika

(Institute of Molecular Genetics, Czech Academy of Sciences, 14220 Prague, Czech Republic)

About Institute of Molecular Genetics, Czech Academy of Sciences, 14220 Prague, Czech Republic

, 
Lejckova Barbora

About Lejckova Barbora

(BIOPHARM, Research Institute of Biopharmacy and Veterinary Drugs, 254 49 Jilove u Prahy, Czech Republic)

About BIOPHARM, Research Institute of Biopharmacy and Veterinary Drugs, 254 49 Jilove u Prahy, Czech Republic

, 
Hejnar Jiri

About Hejnar Jiri

(Institute of Molecular Genetics, Czech Academy of Sciences, 14220 Prague, Czech Republic)

About Institute of Molecular Genetics, Czech Academy of Sciences, 14220 Prague, Czech Republic


Material：
Proceedings of the National Academy of Sciences of the United States of America  (PNAS)

About Proceedings of the National Academy of Sciences of the United States of America


Volume： 117  Issue： 4  Page： 2108-2112  Publication year： 2020 
JST Material Number： D0387A  ISSN： 0027-8424  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)
Abstract/Point：
Abstract/Point
Japanese summary of the article(about several hundred characters).
All summary is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
Avian leukosis virus subgroup ...
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Thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
poultry

About poultry

, 
*gene

About gene

, 
sensitivity

About sensitivity

, 
wild type

About wild type

, 
reproductive cell

About reproductive cell

, 
in vitro experiment

About in vitro experiment

, 
receptor

About receptor

, 
food

About food

, 
amino acid

About amino acid

, 
*avian leukovirus

About avian leukovirus

, 
side effect

About side effect

, 
antiviral action

About antiviral action


Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
遺伝子編集

About 遺伝子編集

, 
始原生殖細胞

About 始原生殖細胞

, 
*Cas9

About Cas9

, 【Automatic Indexing@JST】
Author keywords (5)：
avian leukosis virus subgroup J

About avian leukosis virus subgroup J

, 
Na+/H+ exchanger type 1

About Na+/H+ exchanger type 1

, 
CRISPR/Cas9 genome editing in chicken

About CRISPR/Cas9 genome editing in chicken

, 
primordial germ cells

About primordial germ cells

, 
disease resilience in poultry

About disease resilience in poultry

JST classification (1)：
JST classification
Category name(code) classified by JST.
Gene manipulation 
(EC02050B)

About Gene manipulation

Terms in the title (9)：
Terms in the title
Keywords automatically extracted from the title.
NHE1

About NHE1

, 
遺伝子

About 遺伝子

, 
CRISPR

About CRISPR

, 
Cas9

About Cas9

, 
エディティング

About エディティング

, 
トリ白血病ウイルス

About トリ白血病ウイルス

, 
サブ

About サブ

, 
グループ

About グループ

, 
耐性

About 耐性


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