Art

J-GLOBAL ID：202002256171740446   Reference number：20A1739569

The Tumor Microenvironment: A Milieu Hindering and Obstructing Antitumor Immune Responses

腫瘍微小環境:Milieuの妨害と抗腫瘍免疫応答の妨害【JST・京大機械翻訳】

Author (3)： Labani-Motlagh Alireza (Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden) ,  Ashja-Mahdavi Mehrnoush (Department of Molecular Biology, Umea University, Umea, Sweden) ,  Loskog Angelica (Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden)
Material： Frontiers in Immunology (Web)
Volume： 11  Page： 940  Publication year： 2020 
JST Material Number： U7074A  ISSN： 1664-3224  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： The success of cancer immunoth...

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Thesaurus term： optimization ,  network ,  immersional wetting ,  interstitial tissue ,  *tumor ,  *immunological reaction ,  immunotherapy ,  *tumor immunity
Semi thesaurus term： 癌免疫療法 ,  エキソソーム ,  免疫細胞 ,  免疫回避 ,  免疫活性化 ,  *腫瘍内微小環境 , 【Automatic Indexing@JST】

Author keywords (6)： tumor ,  tumor microenvironment ,  immune cells ,  immune response ,  immunosuppression ,  antitumor

JST classification (5)： Immunotherapy for tumors  (GE03035B) ,  Tumor immunity  (ED03040A) ,  Basic oncology in general  (GE02010R) ,  Basic research of immunotherapeutic agents and blood preparations  (GW22010D) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Reference (282)：

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• Martin JH, Edwards SW. Changes in mechanisms of monocyte/macrophage-mediated cytotoxicity during culture. Reactive oxygen intermediates are involved in monocyte-mediated cytotoxicity, whereas reactive nitrogen intermediates are employed by macrophages in tumor cell killing. J Immunol. (1993) 150:3478-86. doi: 10.1172/JCI66776
• Urban JL, Shepard HM, Rothstein JL, Sugarman BJ, Schreiber H. Tumor necrosis factor: a potent effector molecule for tumor cell killing by activated macrophages. Proc Natl Acad Sci USA. (1986) 83:5233-37. doi: 10.1073/pnas.83.14.5233
• Sektioglu IM, Carretero R, Bulbuc N, Bald T, Tuting T, Rudensky AY, et al. Basophils promote tumor rejection via chemotaxis and infiltration of CD8+ T cells. Cancer Res. (2017) 77:291-302. doi: 10.1158/0008-5472.CAN-16-0993

Terms in the title (4)： 腫瘍微小環境 ,  妨害 ,  抗腫瘍免疫 ,  応答