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J-GLOBAL ID：202002257061581147   Reference number：20A0707784

Flavonoid Compounds Contained in Epimedii Herba Inhibit Tumor Progression by Suppressing STAT3 Activation in the Tumor Microenvironment

Epimedii herbaに含まれるフラボノイド化合物は腫瘍微小環境におけるSTAT3活性化を抑制することにより腫瘍進行を阻害する【JST・京大機械翻訳】

Author (11)： Pan Cheng (Department of Cell Pathology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Fujiwara Yukio (Department of Cell Pathology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Horlad Hasita (Department of Cell Pathology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Shiraishi Daisuke (Department of Cell Pathology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Shiraishi Daisuke (Department of Orthopedic Surgery, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Iriki Toyohisa (Department of Cell Pathology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Iriki Toyohisa (Department of Respiratory Medicine, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Tsuboki Jyunko (Department of Cell Pathology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Tsuboki Jyunko (Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Ikeda Tsuyoshi (Faculty of Pharmaceutical Sciences, Sojo University, Kumamoto, Japan) ,  Komohara Yoshihiro (Department of Cell Pathology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan)
Material： Frontiers in Pharmacology (Web)
Volume： 11  Page： 262  Publication year： 2020 
JST Material Number： U7091A  ISSN： 1663-9812  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： M2-like tumor-associated macro...

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Thesaurus term： *flavonoid ,  cell proliferation ,  targeting ,  sarcoma ,  human(primates) ,  tumor cell ,  interleukin ,  phenotype ,  macrophage ,  tumorigenesis ,  polarization(phenomenon) ,  animal
Semi thesaurus term： 担癌マウス ,  CD163 ,  *腫瘍進行 , 【Automatic Indexing@JST】

Author keywords (5)： Epimedii Herba ,  STAT3 ,  flavonoid ,  macrophage ,  tumor cells

JST classification (5)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Tumor immunity  (ED03040A) ,  Cell physiology in general  (EF02010S) ,  Biophylaxis and immune systems in general  (ED01010F) ,  Basic oncology in general  (GE02010R)

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Terms in the title (6)： フラボノイド ,  腫瘍微小環境 ,  STAT3 ,  活性化 ,  腫瘍進行 ,  阻害