Art

J-GLOBAL ID：202002257635285185   Reference number：20A1117184

Excessive folic acid supplementation in pregnant mice impairs insulin secretion and induces the expression of genes associated with fatty liver in their offspring

妊娠マウスにおける過剰葉酸補給は,インスリン分泌を損ない,その子孫における脂肪肝と関連した遺伝子発現を誘導する【JST・京大機械翻訳】

Author (9)： Kintaka Yuri (Department of Food and Nutrition, Faculty of Human Life, Jumonji University, Saitama, Japan) ,  Kintaka Yuri (Institute of International Nutrition and Health, Jumonji University, Saitama, Japan) ,  Wada Nobuhiro (Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Shioda Seiji (Peptide Drug Innovation, Global Research Center for Innovative Life Science, Hoshi University, Tokyo, Japan) ,  Nakamura Sadako (Department of Food and Nutrition, Faculty of Human Life, Jumonji University, Saitama, Japan) ,  Nakamura Sadako (Institute of International Nutrition and Health, Jumonji University, Saitama, Japan) ,  Yamazaki Yuko (Department of Food and Nutrition, Faculty of Human Life, Jumonji University, Saitama, Japan) ,  Yamazaki Yuko (Institute of International Nutrition and Health, Jumonji University, Saitama, Japan) ,  Mochizuki Kazuki (Laboratory of Food and Nutritional Sciences, Department of Local Produce and Food Sciences, Faculty of Life and Environmental Sciences, University of Yamanashi, Yamanashi, Japan)
Material： Heliyon
Volume： 6  Issue： 4  Page： Null  Publication year： 2020 
JST Material Number： W3098A  ISSN： 2405-8440  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Previous human and animal stud...

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Thesaurus term： triglyceride ,  *gene ,  *insulin ,  serum ,  blood glucose ,  *fatty liver ,  *pregnancy ,  human(primates) ,  *gene expression ,  sugar tolerance ,  amino acid ,  aliphatic amine ,  nitrogen heterocyclic compound ,  aromatic amine ,  aromatic carboxylic acid ,  aliphatic carboxylic acid ,  vitamin B family ,  carboxamide ,  hydroxy compound ,  aminocarboxylic acid ,  secondary amine
Semi thesaurus term： *インスリン分泌 ,  耐糖能 ,  経口ぶどう糖負荷試験 ,  mRNA発現 , 【Automatic Indexing@JST】

Author keywords (10)： Biochemistry ,  Nutrition ,  Health sciences ,  Pregnancy ,  Metabolism ,  Metabolic disorder ,  Folic acid ,  Insulin ,  Impaired glucose tolerance ,  Fat metabolism

JST classification (4)： Vitamin B group  (EB07030L) ,  Metabolic diseases,nutritional diseases in general.  (GD05010J) ,  Food chemistry,nutritional value  (FJ01020J) ,  Development(=generation)and differentiation  (EJ16020W)

Substance index (1)： Folic Acid

Terms in the title (7)： 妊娠マウス ,  葉酸 ,  補給 ,  インスリン分泌 ,  脂肪肝 ,  遺伝子発現 ,  誘導