Art

J-GLOBAL ID：202002258817384071   Reference number：20A1740158

Extracellular Vesicles in Renal Cell Carcinoma: Multifaceted Roles and Potential Applications Identified by Experimental and Computational Methods

腎細胞癌における細胞外小胞:実験的および計算的方法により同定された多面的役割と潜在的応用【JST・京大機械翻訳】

Author (5)： Qin Zhiyuan (College of Pharmaceutical Sciences, Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang University, Hangzhou, China) ,  Xu Qingwen (College of Pharmaceutical Sciences, Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang University, Hangzhou, China) ,  Hu Haihong (College of Pharmaceutical Sciences, Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang University, Hangzhou, China) ,  Yu Lushan (College of Pharmaceutical Sciences, Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang University, Hangzhou, China) ,  Zeng Su (College of Pharmaceutical Sciences, Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang University, Hangzhou, China)
Material： Frontiers in Oncology (Web)
Volume： 10  Page： 724  Publication year： 2020 
JST Material Number： U7089A  ISSN： 2234-943X  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Renal cell carcinoma (RCC) is ...

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Thesaurus term： DNA ,  RNA ,  lipid ,  biodistribution ,  protein ,  drug resistance ,  artificial intelligence ,  biological activity ,  biocompatibility ,  *renal cell carcinoma ,  biomarker ,  tumorigenesis
Semi thesaurus term： 細胞間コミュニケーション ,  免疫回避 ,  *細胞外小胞 , 【Automatic Indexing@JST】

Author keywords (8)： renal cell carcinoma ,  extracellular vesicles ,  exosomes ,  biomarkers ,  drug targets ,  drug vehicles ,  artificial intelligence ,  machine learning

JST classification (3)： Function of cell components  (EF03060C) ,  Cell physiology in general  (EF02010S) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Reference (159)：

• Shuch B, Amin A, Armstrong AJ, Eble JN, Ficarra V, Lopez-Beltran A, et al. Understanding pathologic variants of renal cell carcinoma: distilling therapeutic opportunities from biologic complexity. Eur Urol. (2015) 67:85-97. doi: 10.1016/j.eururo.2014.04.029
• Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. (2018) 68:394-424. doi: 10.3322/caac.21492
• Siegel RL, Miller KD, Jemal A. Cancer statistics, 2020. CA Cancer J Clin. (2020) 70:7-30. doi: 10.3322/caac.21590
• Surveillance Epidemiology End Results Program. SEER Stat Fact Sheets: Kidney and Renal Pelvis Cancer. Bethesda, MD: National Cancer Institute. Available online at: https://seer.cancer.gov/statfacts/html/kidrp.html (accessed December 20, 2019). doi: 10.3322/caac.21590
• Choueiri TK, Motzer RJ. Systemic therapy for metastatic renal-cell carcinoma. N Engl J Med. (2017) 376:354-66. doi: 10.1056/NEJMra1601333

Terms in the title (7)： 腎細胞癌 ,  細胞外小胞 ,  実験 ,  計算 ,  同定 ,  役割 ,  応用