Art

J-GLOBAL ID：202002258908918518   Reference number：20A0527815

Shear stress stimulates integrin β1 trafficking and increases directional migration of cancer cells via promoting deacetylation of microtubules

せん断応力はインテグリンβ1輸送を刺激し,微小管の脱アセチル化を促進することにより癌細胞の指向性移動を増加させる【JST・京大機械翻訳】

Author (23)： Tang Kai (Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, PR China) ,  Li Shun (Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, PR China) ,  Li Shun (Center for Information in Biology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, PR China) ,  Li Ping (Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, PR China) ,  Xia Qiong (Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, PR China) ,  Yang Rui (Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, PR China) ,  Li Tingting (Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, PR China) ,  Li Tingting (Center for Information in Biology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, PR China) ,  Li Li (Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, PR China) ,  Li Li (Center for Information in Biology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, PR China) ,  Jiang Ying (Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, PR China) ,  Jiang Ying (Center for Information in Biology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, PR China) ,  Qin Xiang (Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, PR China) ,  Qin Xiang (Center for Information in Biology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, PR China) ,  Yang Hong (Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, PR China) ,  Yang Hong (Center for Information in Biology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, PR China) ,  Wu Chunhui (Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, PR China) ,  Wu Chunhui (Center for Information in Biology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, PR China) ,  You Fengming (Hospital of Chengdu University of Traditional Chinese Medicine, No. 39 Shi-er-qiao Road, Chengdu 610072, Sichuan, PR China) ,  Tan Youhua (The Hong Kong Polytechnic University Shenzhen Research Institute, Shenzhen, PR China) ,  Tan Youhua (Department of Biomedical Engineering, The Hong Kong Polytechnic University, Hong Kong, PR China) ,  Liu Yiyao (Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, PR China) ,  Liu Yiyao (Hospital of Chengdu University of Traditional Chinese Medicine, No. 39 Shi-er-qiao Road, Chengdu 610072, Sichuan, PR China)
Material： Biochimica et Biophysica Acta  (BBA. Biomembranes)
Volume： 1867  Issue： 5  Page： Null  Publication year： 2020 
JST Material Number： B0207A  ISSN： 0005-2728  CODEN： BBBMBS  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： In egress routes of malignancy...

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Thesaurus term： internalization ,  *tumor cell ,  endocytosis ,  *microtubule ,  *shear(mechanics) ,  cell migration ,  *integrin ,  cytoskeleton ,  *acetylation ,  turnover ,  breast tumor ,  *shearing stress ,  cell adhesion ,  down-regulation ,  *deacetylation

Author keywords (5)： Integrin internalization and recycling ,  Caveolin-1 ,  Focal adhesion turnover ,  Microtubule deacetylation ,  HDAC6

JST classification (2)： Cell physiology in general  (EF02010S) ,  Biological function  (EB03040U)

Terms in the title (9)： せん断応力 ,  インテグリンβ1 ,  輸送 ,  刺激 ,  微小管 ,  脱アセチル化 ,  促進 ,  癌細胞 ,  指向性