Art

J-GLOBAL ID：202002259134694411   Reference number：20A0407377

Abemaciclib, a CDK4/6 inhibitor, exerts preclinical activity against aggressive germinal center-derived B-cell lymphomas

CDK4/6阻害剤アベマシクリブは侵攻性胚中心由来B細胞リンパ腫に対して前臨床活性を発揮する

Author (12)： Tanaka Yuka (Department of Hematology, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan) ,  Momose Shuji (Department of Pathology, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan) ,  Momose Shuji (Institute of Pathology, Comprehensive Cancer Center Mainfranken, University of Wuerzburg, Wuerzburg, Germany) ,  Tabayashi Takayuki (Department of Hematology, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan) ,  Sawada Keisuke (Department of Pathology, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan) ,  Yamashita Takahisa (Department of Pathology, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan) ,  Higashi Morihiro (Department of Pathology, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan) ,  Sagawa Morihiko (Department of Hematology, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan) ,  Tokuhira Michihide (Department of Hematology, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan) ,  Rosenwald Andreas (Institute of Pathology, Comprehensive Cancer Center Mainfranken, University of Wuerzburg, Wuerzburg, Germany) ,  Kizaki Masahiro (Department of Hematology, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan) ,  Tamaru Jun-ichi (Department of Pathology, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan)
Material： Cancer Science (Web)  (Cancer Sci (Web))
Volume： 111  Issue： 2  Page： 749-759  Publication year： 2020 
JST Material Number： U0505A  ISSN： 1349-7006  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *enzyme inhibitor ,...
Semi thesaurus term： Cdk4 kinase ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=20A0407377&from=J-GLOBAL&jstjournalNo=U0505A") }}

Author keywords (5)： B-cell lymphoma ,  CDK4/6 inhibitor ,  cyclin D3 ,  high-grade B-cell lymphoma ,  MYC

JST classification (2)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Experimental treatment for tumors  (GE02040Y)

Substance index (2)： Abemaciclib ,  Palbociclib

Terms in the title (8)： Cdk4 ,  阻害剤 ,  アベマシクリブ ,  侵攻 ,  胚中心 ,  B細胞リンパ腫 ,  臨床 ,  活性