Art

J-GLOBAL ID：202002259656040899   Reference number：20A0709769

Cyp2c44 regulates prostaglandin synthesis, lymphangiogenesis, and metastasis in a mouse model of breast cancer

CYP2C44は乳癌のマウスモデルにおけるプロスタグランジン合成,リンパ管形成および転移を調節する【JST・京大機械翻訳】

Author (20)： Kesavan Rushendhiran (Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe-University, 60590 Frankfurt am Main, Germany) ,  Fromel Timo (Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe-University, 60590 Frankfurt am Main, Germany) ,  Fromel Timo (German Centre for Cardiovascular Research (DZHK), Partner Site RheinMain, 60590 Frankfurt, Germany) ,  Zukunft Sven (Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe-University, 60590 Frankfurt am Main, Germany) ,  Zukunft Sven (German Centre for Cardiovascular Research (DZHK), Partner Site RheinMain, 60590 Frankfurt, Germany) ,  Laban Hebatullah (Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe-University, 60590 Frankfurt am Main, Germany) ,  Laban Hebatullah (German Centre for Cardiovascular Research (DZHK), Partner Site RheinMain, 60590 Frankfurt, Germany) ,  Geyer Alexandra (Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe-University, 60590 Frankfurt am Main, Germany) ,  Naeem Zumer (Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe-University, 60590 Frankfurt am Main, Germany) ,  Heidler Juliana (German Centre for Cardiovascular Research (DZHK), Partner Site RheinMain, 60590 Frankfurt, Germany) ,  Heidler Juliana (Functional Proteomics, Sonderforschungsbereich (SFB) 815 Core Unit, Faculty of Medicine, Goethe University, 60590 Frankfurt am Main, Germany) ,  Wittig Ilka (German Centre for Cardiovascular Research (DZHK), Partner Site RheinMain, 60590 Frankfurt, Germany) ,  Wittig Ilka (Functional Proteomics, Sonderforschungsbereich (SFB) 815 Core Unit, Faculty of Medicine, Goethe University, 60590 Frankfurt am Main, Germany) ,  Elwakeel Eiman (Institute of Biochemistry I, Goethe-University, 60590 Frankfurt am Main, Germany) ,  Bruene Bernhard (Institute of Biochemistry I, Goethe-University, 60590 Frankfurt am Main, Germany) ,  Weigert Andreas (Institute of Biochemistry I, Goethe-University, 60590 Frankfurt am Main, Germany) ,  Popp Ruediger (Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe-University, 60590 Frankfurt am Main, Germany) ,  Popp Ruediger (German Centre for Cardiovascular Research (DZHK), Partner Site RheinMain, 60590 Frankfurt, Germany) ,  Fleming Ingrid (Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe-University, 60590 Frankfurt am Main, Germany) ,  Fleming Ingrid (German Centre for Cardiovascular Research (DZHK), Partner Site RheinMain, 60590 Frankfurt, Germany)
Material： Proceedings of the National Academy of Sciences of the United States of America  (PNAS)
Volume： 117  Issue： 11  Page： 5923-5930  Publication year： 2020 
JST Material Number： D0387A  ISSN： 0027-8424  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Arachidonic acid epoxides gene...

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Thesaurus term： macrophage ,  phosphorylation ,  Toll like receptor ,  diol ,  down-regulation ,  cellular signal transduction ,  genotype ,  NF-kappaB ,  *prostaglandin ,  up-regulation ,  *breast tumor ,  *lymph ,  oncogene ,  precursor(substance) ,  tumor

Author keywords (4)： cytochrome P450 ,  WDFY1 ,  metastasis ,  lymphangiogenesis

JST classification (1)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Terms in the title (5)： 乳癌 ,  マウスモデル ,  プロスタグランジン ,  リンパ管形成 ,  調節