Art

J-GLOBAL ID：202002259782711201   Reference number：20A0772134

Endosome-Mediated Epithelial Remodeling Downstream of Hedgehog-Gli Is Required for Tracheoesophageal Separation

Hedgehog-Gliの下流のエンドソーム仲介上皮リモデリングは気管食道分離に必要である【JST・京大機械翻訳】

Author (20)： Nasr Talia (Center for Stem Cell and Organoid Medicine, CuSTOM, Division of Developmental Biology, and Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45219, USA) ,  Nasr Talia (Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45219, USA) ,  Mancini Pamela (Center for Stem Cell and Organoid Medicine, CuSTOM, Division of Developmental Biology, and Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45219, USA) ,  Rankin Scott A. (Center for Stem Cell and Organoid Medicine, CuSTOM, Division of Developmental Biology, and Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45219, USA) ,  Edwards Nicole A. (Center for Stem Cell and Organoid Medicine, CuSTOM, Division of Developmental Biology, and Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45219, USA) ,  Agricola Zachary N. (Division of Neonatology and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45219, USA) ,  Kenny Alan P. (Division of Neonatology and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45219, USA) ,  Kinney Jessica L. (Center for Stem Cell and Organoid Medicine, CuSTOM, Division of Developmental Biology, and Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45219, USA) ,  Daniels Keziah (Center for Stem Cell and Organoid Medicine, CuSTOM, Division of Developmental Biology, and Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45219, USA) ,  Vardanyan Jon (Center for Stem Cell and Organoid Medicine, CuSTOM, Division of Developmental Biology, and Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45219, USA) ,  Han Lu (Center for Stem Cell and Organoid Medicine, CuSTOM, Division of Developmental Biology, and Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45219, USA) ,  Trisno Stephen L. (Center for Stem Cell and Organoid Medicine, CuSTOM, Division of Developmental Biology, and Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45219, USA) ,  Trisno Stephen L. (Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45219, USA) ,  Cha Sang-Wook (Center for Stem Cell and Organoid Medicine, CuSTOM, Division of Developmental Biology, and Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45219, USA) ,  Wells James M. (Center for Stem Cell and Organoid Medicine, CuSTOM, Division of Developmental Biology, and Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45219, USA) ,  Wells James M. (Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45219, USA) ,  Kofron Matthew J. (Center for Stem Cell and Organoid Medicine, CuSTOM, Division of Developmental Biology, and Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45219, USA) ,  Kofron Matthew J. (Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45219, USA) ,  Zorn Aaron M. (Center for Stem Cell and Organoid Medicine, CuSTOM, Division of Developmental Biology, and Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45219, USA) ,  Zorn Aaron M. (Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45219, USA)
Material： Developmental Cell  (Dev Cell)
Volume： 51  Issue： 6  Page： 665-674.e6  Publication year： 2019 
JST Material Number： W1692A  ISSN： 1534-5807  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： The trachea and esophagus aris...

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Thesaurus term： *trachea(animal organ) ,  *epithelium ,  fetus ,  mutation ,  human(primates) ,  *esophagus ,  morphogenesis ,  GTPase ,  Xenopus laevis ,  mesenchyme ,  extracellular matrix ,  *endosome
Semi thesaurus term： Sox2 ,  共発現 ,  前腸 , 【Automatic Indexing@JST】

Author keywords (3)： esophageal atresia ,  EA/TEF ,  Sox2

JST classification (3)： Cell physiology in general  (EF02010S) ,  Development(=generation)and differentiation  (EJ16020W) ,  Biological function  (EB03040U)

Terms in the title (9)： hedgehog ,  GLI ,  下流 ,  エンドソーム ,  仲介 ,  上皮 ,  リモデリング ,  気管 ,  食道