Art

J-GLOBAL ID：202002259953486855   Reference number：20A0477675

Crotoxin down-modulates pro-inflammatory cells and alleviates pain on the MOG_35-55-induced experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis

クロトキシンは多発性硬化症の動物モデルであるMOG_35-55誘発実験的自己免疫性脳脊髄炎における炎症促進性細胞を下方制御し疼痛を軽減する【JST・京大機械翻訳】

Author (8)： Teixeira N.B. (Laboratory of Pain and Signaling, Butantan Institute, Sao Paulo, Brazil) ,  Sant'Anna M.B. (Laboratory of Pain and Signaling, Butantan Institute, Sao Paulo, Brazil) ,  Giardini A.C. (Laboratory of Pain and Signaling, Butantan Institute, Sao Paulo, Brazil) ,  Araujo L.P. (Department of Microbiology, Immunology and Parasitology, Paulista School of Medicine, Federal University of Sao Paulo, UNIFESP, Sao Paulo, Brazil) ,  Fonseca L.A. (Laboratory of Pain and Signaling, Butantan Institute, Sao Paulo, Brazil) ,  Basso A.S. (Department of Microbiology, Immunology and Parasitology, Paulista School of Medicine, Federal University of Sao Paulo, UNIFESP, Sao Paulo, Brazil) ,  Cury Y. (Laboratory of Pain and Signaling, Butantan Institute, Sao Paulo, Brazil) ,  Picolo G. (Laboratory of Pain and Signaling, Butantan Institute, Sao Paulo, Brazil)
Material： Brain, Behavior, and Immunity  (Brain Behavior and Immunity)
Volume： 84  Page： 253-268  Publication year： 2020 
JST Material Number： W1766A  ISSN： 0889-1591  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Multiple sclerosis (MS) is a C...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=20A0477675&from=J-GLOBAL&jstjournalNo=W1766A") }}

Thesaurus term： single administration ,  *pain ,  anti-inflammatory action ,  *inflammation ,  antinociceptive action ,  microglia ,  Th1 cell ,  movement disorder ,  interaction ,  macrophage ,  *multiple sclerosis ,  in vitro experiment ,  *down-regulation ,  *spinal cord ,  neuron

Author keywords (5)： Crotoxin ,  Multiple sclerosis ,  Experimental autoimmune encephalomyelitis ,  Analgesia ,  Immunomodulatory effect

JST classification (1)： Basic neurology  (GN01020W)

Terms in the title (11)： クロトキシン ,  多発性硬化症 ,  動物 ,  モデル ,  誘発 ,  実験的自己免疫性脳脊髄炎 ,  炎症 ,  促進 ,  性細胞 ,  下方制御 ,  疼痛