Art
J-GLOBAL ID：202002260275247859   Reference number：20A1551707

TDP2 suppresses genomic instability induced by androgens in the epithelial cells of prostate glands

TDP2は前立腺の上皮細胞でアンドロゲンにより誘導されるゲノム不安定性を抑制する
Author (12)：
Al Mahmud Md. Rasel

About Al Mahmud Md. Rasel

(Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto, Japan)

About Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto, Japan

, 
Ishii Kenichiro

About Ishii Kenichiro

(Department of Oncologic Pathology, Mie University Graduate School of Medicine, Tsu, Japan)

About Department of Oncologic Pathology, Mie University Graduate School of Medicine, Tsu, Japan

, 
Bernal-Lozano Cristina

About Bernal-Lozano Cristina

(Centro Andaluz de Biologia Molecular y Medicina Regenerativa (CABIMER), CSIC-Universidad de Sevilla Universidad Pablo de Olavide, Sevilla, Spain)

About Centro Andaluz de Biologia Molecular y Medicina Regenerativa (CABIMER), CSIC-Universidad de Sevilla Universidad Pablo de Olavide, Sevilla, Spain

, 
Delgado-Sainz Irene

About Delgado-Sainz Irene

(Centro Andaluz de Biologia Molecular y Medicina Regenerativa (CABIMER), CSIC-Universidad de Sevilla Universidad Pablo de Olavide, Sevilla, Spain)

About Centro Andaluz de Biologia Molecular y Medicina Regenerativa (CABIMER), CSIC-Universidad de Sevilla Universidad Pablo de Olavide, Sevilla, Spain

, 
Toi Masakazu

About Toi Masakazu

(Department of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan)

About Department of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

, 
Akamatsu Shusuke

About Akamatsu Shusuke

(Department of Urology, Graduate School of Medicine, Kyoto University, Kyoto, Japan)

About Department of Urology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

, 
Fukumoto Manabu

About Fukumoto Manabu

(RIKEN Center for Advanced Intelligence Project, Tokyo, Japan)

About RIKEN Center for Advanced Intelligence Project, Tokyo, Japan

, 
Watanabe Masatoshi

About Watanabe Masatoshi

(Department of Oncologic Pathology, Mie University Graduate School of Medicine, Tsu, Japan)

About Department of Oncologic Pathology, Mie University Graduate School of Medicine, Tsu, Japan

, 
Takeda Shunichi

About Takeda Shunichi

(Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto, Japan)

About Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto, Japan

, 
Cortes-Ledesma Felipe

About Cortes-Ledesma Felipe

(Centro Andaluz de Biologia Molecular y Medicina Regenerativa (CABIMER), CSIC-Universidad de Sevilla Universidad Pablo de Olavide, Sevilla, Spain)

About Centro Andaluz de Biologia Molecular y Medicina Regenerativa (CABIMER), CSIC-Universidad de Sevilla Universidad Pablo de Olavide, Sevilla, Spain

, 
Cortes-Ledesma Felipe

About Cortes-Ledesma Felipe

(Topology and DNA Breaks Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain)

About Topology and DNA Breaks Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain

, 
Sasanuma Hiroyuki

About Sasanuma Hiroyuki

(Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto, Japan)

About Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto, Japan


Material：
Genes to Cells  (Genes Cells)

About Genes to Cells


Volume： 25  Issue： 7  Page： 450-465  Publication year： Jul. 2020 
JST Material Number： W0935A  ISSN： 1356-9597  CODEN： GECEFL  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)
Thesaurus term：
Thesaurus term/Semi thesaurus term
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*phosphodiesterase

About phosphodiesterase

,...
Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
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LNCaP cell

About LNCaP cell

,...
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Author keywords (6)：
androgen

About androgen

, 
atypical epithelial hyperplasia

About atypical epithelial hyperplasia

, 
DNA double-strand break

About DNA double-strand break

, 
prostatic intraepithelial neoplasia

About prostatic intraepithelial neoplasia

, 
TDP2

About TDP2

, 
topoisomerase 2

About topoisomerase 2

JST classification (4)：
JST classification
Category name(code) classified by JST.
Basic medicine on endocrine system 
(GL01020Q)

About Basic medicine on endocrine system

,  Sex hormones 
(EB08050O)

About Sex hormones

,  Molecular genetics in general 
(EC02010J)

About Molecular genetics in general

,  Enzyme in general 
(EB09010D)

About Enzyme in general

Terms in the title (5)：
Terms in the title
Keywords automatically extracted from the title.
前立腺

About 前立腺

, 
上皮細胞

About 上皮細胞

, 
アンドロゲン

About アンドロゲン

, 
誘導

About 誘導

, 
ゲノム不安定性

About ゲノム不安定性


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